{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:32:00Z","timestamp":1783384320494,"version":"3.54.6"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T00:00:00Z","timestamp":1682726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Intertransverse process (ITP) blocks are applied on the posterior side of the thoracic paravertebral space. The modality is described as being a paravertebral block by proxy, possibly providing a similar analgesic effect as the thoracic paravertebral block. However, systematic evidence on anaesthetised dermatomes and the extent of cutaneous sensory loss following ITP blocks is sparse. This study aims to test the single\u2010 versus the multiple\u2010injection ITP block. The primary outcome is the number of anaesthetised thoracic dermatomes for each block type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twelve healthy male volunteers will participate in this randomised, procedure\u2010related, double\u2010blinded, non\u2010inferiority crossover trial after informed consent. Blinded participants will receive either a unilateral single\u2010injection ITP block with 21\u2009mL ropivacaine 7.5\u2009mg\/mL including two sham blocks or a unilateral multiple\u2010injection ITP block with 3 \u00d7\u20097\u2009mL ropivacaine 7.5\u2009mg\/mL on study Day 1, and the other modality on study Day 2. Block applicants will be blinded from outcome assessment and vice versa. Following block application sensory test by mechanical pinprick and temperature discrimination will be performed. Anterior truncal thermography will be measured three times after block application to compare skin temperature in the mid\u2010clavicular line between the blocked and the contralateral non\u2010blocked hemithorax. In addition, blood pressure changes are measured three times non\u2010invasively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The current study will provide substantial knowledge regarding the cutaneous sensory loss of the ITP block. Furthermore, the study might provide insight regarding the possible clinical usage of thermography as a reliable instrument for measuring nerve block efficacy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.14248","type":"journal-article","created":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T07:49:46Z","timestamp":1682754586000},"page":"987-992","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The intertransverse process block single\u2010 or multiple\u2010injection? A study protocol"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1309-6035","authenticated-orcid":false,"given":"Amanda","family":"de la Fuente Birkeb\u00e6k","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8086-5757","authenticated-orcid":false,"given":"Katrine","family":"Tanggaard","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7493-9665","authenticated-orcid":false,"given":"Sophie","family":"Bojesen","sequence":"additional","affiliation":[{"name":"Department of Plastic and Breast Surgery Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1577-5437","authenticated-orcid":false,"given":"Anne Sofie","family":"Therkelsen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4228-3364","authenticated-orcid":false,"given":"Cecilie H.","family":"Klementsen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1719-9402","authenticated-orcid":false,"given":"Christian K.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan","family":"Vazin","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troels Dirch","family":"Poulsen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9839-3812","authenticated-orcid":false,"given":"Jens","family":"B\u00f8rglum","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Clinical Science University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3764-0445","authenticated-orcid":false,"given":"Martin V.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/rapm\u20102020\u2010102451"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/rapm\u20102022\u2010104012"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1213\/XAA.0000000000001610"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/rapm\u20102022\u2010104003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000436117.52143.bc"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2014.11.006"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2021.12.036"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000252"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12871\u2010021\u201001389\u20104"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.46292\/sci2702\u20101"},{"key":"e_1_2_7_12_1","unstructured":"Sketchandcalc [computer software]. 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