{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T13:38:39Z","timestamp":1777815519216,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Persistent opioid use following surgery is common especially in patients with preoperative opioid use. This study aims to determine the long\u2010term effect of an individualised opioid tapering plan versus standard of care in patients with a preoperative opioid use undergoing spine surgery at Aarhus University Hospital, Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is the 1\u2010year follow\u2010up of a prospective, single\u2010centre, randomised trial of 110 patients who underwent elective spine surgery for degenerative disease. The intervention was an individualised tapering plan at discharge and telephone counselling 1\u2009week after discharge, compared to standard of care. Postoperative outcomes after 1\u2009year include opioid use, reasons for opioid use and pain intensity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall response rate to the 1\u2010year follow\u2010up questionnaire was 94% (intervention group 52\/55 patients and control group 51\/55 patients). Forty\u2010two patients (proportion\u2009=\u20090.81, 95% CI 0.67\u20130.89) in the intervention group compared to 31 (0.61, 95% CI 0.47\u20130.73; <jats:italic>p<\/jats:italic>\u2009=\u2009.026) patients in the control group succeeded in tapering to zero 1\u2009year after discharge (<jats:italic>p<\/jats:italic>\u2009=\u2009.026). One patient (0.02, 95% CI 0.01\u20130.13) in the intervention group compared to seven patients (0.14, 95% CI 0.07\u20130.26) in the control group were unable to taper to their preoperative dose 1\u2009year after discharge (<jats:italic>p<\/jats:italic>\u2009=\u2009.025). Back\/neck and radicular pain intensity was similar between study groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These results suggest that an individualised tapering plan at discharge combined with telephone counselling 1\u2009week after discharge can reduce opioid use 1\u2009year after spine surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.14266","type":"journal-article","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T05:23:36Z","timestamp":1684473816000},"page":"1085-1090","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["An individualised tapering protocol reduces opioid use 1\u2009year after spine surgery: A randomised controlled trial of patients with preoperative opioid use"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2560-1705","authenticated-orcid":false,"given":"Peter 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