{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T09:37:23Z","timestamp":1771234643331,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Optimizing pain management following cesarean section is crucial for the well\u2010being of both mother and infant. Various types of quadratus lumborum blocks have exhibited reduced opioid consumption and pain scores after cesarean section. However, duration of block effect is relatively short. The aim of this study was to investigate the analgesic efficacy of the anterior quadratus lumborum catheters for cesarean section.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All 32 enrolled participants were allocated to postoperative bilateral ultrasound\u2010guided anterior quadratus lumborum catheter placement with injection of 60\u2009mL ropivacaine 0.375% after cesarean section. Randomization at 2\u2009h resulted in either 60\u2009mL ropivacaine 0.2% or 60\u2009mL isotonic saline injected through the catheters, with subsequent 22\u2010h infusion of either ropivacaine 0.2% or isotonic saline with an infusion rate of 4\u2009mL\u2009h<jats:sup>\u22121<\/jats:sup> per catheter. Participants in the active group received a total of 697\u2009mg ropivacaine during the first 24\u2009h. All participants received the standard postoperative multimodal pain regimen, and a final bilateral injection at 24\u2010h post\u2010catheter placement of 60\u2009mL ropivacaine 0.375% in total.<\/jats:p><jats:p>The primary outcome was time to first opioid administration. Secondary outcomes were pain scores, time to first ambulation, nausea and vomiting, accumulated opioid consumption, and catheter displacement rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant intergroup differences were observed following the randomized intervention. Median time to first opioid (IQR) was (active vs. placebo) 414 (283, 597) vs. 428 (245, 552) minutes, with a median difference (CI) of \u221214 (\u2212184 to 262) min, <jats:italic>p<\/jats:italic>\u2009=\u2009.32.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Bilateral anterior quadratus lumborum catheters with continuous infusion did not prolong time to first opioid after elective cesarean section.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aas.14335","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T09:21:04Z","timestamp":1696584064000},"page":"254-262","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Anterior quadratus lumborum catheters for elective cesarean section: A double\u2010blind, randomized, placebo\u2010controlled 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