{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T04:05:29Z","timestamp":1767067529530,"version":"3.48.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oral nicotine product (ONP) consumption is constantly increasing while combustible cigar smoking is becoming rare. Possible effects of ONP consumption for early recovery after general anesthesia are poorly recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective single\u2010center study with 151 participants undergoing laparoscopic appendectomy. Incidence of ONP consumption was recorded and consumers were compared to non\u2010consumers intraoperatively and during postanesthesia care unit (PACU) stay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 151 patients 32 (21%, 95% CI, 15%\u201328%) reported regular ONP consumption and it was associated with elevated pain scores (NRS &gt;\u20093) in PACU (2.30 (1.03\u20135.13),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04) whereas the association with postoperative nausea and vomiting occurrence (0.91 (0.34\u20132.47),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.86) or prolonged PACU duration (1.08 (0.39\u20132.94),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.89) was not found.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Based on this study, ONP consumption was associated with higher pain scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Editorial Comment<\/jats:title>\n                    <jats:p>In this study, postlaparscopic appendectomy pain scoring was recorded in a cohort who also reported their habits for oral nicotine product use. In this cohort in Finland, there was an association observed between oral nicotine product use and higher reported pain scores, a larger percentage of cases with NRS scoring over 3.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aas.70163","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T07:01:36Z","timestamp":1765177296000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Consumption of Oral Nicotine Products in Relation to Postanesthesia Care Unit Recovery After Laparoscopic Appendectomy. A Prospective Study"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4053-8078","authenticated-orcid":false,"given":"Juho","family":"Nurkkala","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, Jorvi Hospital  Espoo Finland"},{"name":"Research Unit of Translational Medicine, Research Group of Anesthesiology Oulu University  Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Lampela","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery University of Helsinki and Helsinki University Hospital, Jorvi Hospital  Espoo Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henna","family":"Sammalkorpi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery University of Helsinki and Helsinki University Hospital, Jorvi Hospital  Espoo Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5580-3447","authenticated-orcid":false,"given":"Janne","family":"Liisanantti","sequence":"additional","affiliation":[{"name":"Research Unit of Translational Medicine, Research Group of Anesthesiology Oulu University, Oulu University Hospital, Department of Anesthesiology  Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2603-3807","authenticated-orcid":false,"given":"Vesa","family":"Kontinen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, Jorvi Hospital  Espoo Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexey","family":"Schramko","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, Jorvi Hospital  Espoo Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,7]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2024.01.079"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-025091"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2021.755799"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2009.02140.x"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000014209"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S462112"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/apm-20-2182"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20054526"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/tobaccocontrol-2021-056857"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.16585"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01480545.2021.1925691"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/tc-2022-057280"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntab030"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-022-06172-y"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.20502"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000004000"},{"issue":"1","key":"e_1_2_14_18_1","first-page":"55","article-title":"Pathophysiological and Neurochemical Mechanisms of Postoperative Nausea and Vomiting","volume":"722","author":"Horn C. 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