{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:41:39Z","timestamp":1790739699330,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sternotomy causes substantial postoperative pain. Recently, several less invasive nerve blocks have been described that are safer to use even on anticoagulated patients. This study aims to evaluate early pain management using ultrasound\u2010guided superficial parasternal intercostal plane block (SPIP) in patients undergoing aortic valve replacement via full sternotomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a randomized, placebo\u2010controlled trial performed in a tertiary referral hospital. Seventy\u2010four elective patients scheduled for aortic valve replacement via full sternotomy were included. Patients were randomized to receive a preoperative SPIP block using either 40\u2009mL of ropivacaine 7.5\u2009mg\/mL or 40\u2009mL of 0.9% saline. Cumulative oxycodone consumption during the first 24 postoperative hours was recorded and analyzed as the primary outcome. Pain at rest was assessed using the numerical rating scale (NRS) scores 48\u2009h postoperatively. Additional secondary outcomes included the need for vasopressors and antiemetics, recovery of bowel function, time spent in the intensive care unit (ICU), and nerve block\u2010related complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The 24\u2010h cumulative consumption was not significantly different between groups (93.8\u2009mg\u2009\u00b1\u200933.3 vs. 109.4\u2009mg\u2009\u00b1\u200937.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.066). NRS pain scores at rest were reduced in the patients with SPIP at 4 (5.0\u2009\u00b1\u20091.8 vs. 3.3\u2009\u00b1\u20092.4,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). No differences were found in additional secondary outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this randomized controlled trial a single\u2010shot SPIP block did not reduce the 24\u2010h cumulative opioid consumption after cardiac surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Editorial Comments<\/jats:title>\n                    <jats:p>This trial in a cardiac surgical cohort tested for possible benefit of a single injection superficial parasternal intercostal plane block for post\u2010operative analgesia for post\u2010sternotomy pain. The study found no post\u2010op opioid treatment reduction with the treatment, but some analgesia effect cannot be ruled out.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aas.70253","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T13:45:04Z","timestamp":1778679904000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound\u2010Guided Superficial Parasternal Intercostal Plane Block for Early Pain Management in Patients Undergoing Cardiac Surgery\u2014A Randomized Controlled Trial"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4537-1675","authenticated-orcid":false,"given":"Antti\u2010Johannes","family":"Kalli","sequence":"first","affiliation":[{"name":"Department of Cardiac Anesthesia and Intensive Care Tays Heart Hospital, Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pekka","family":"M\u00e4kel\u00e4","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anesthesia and Intensive Care Tays Heart Hospital, Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1372-430X","authenticated-orcid":false,"given":"Heini","family":"Huhtala","sequence":"additional","affiliation":[{"name":"Faculty of Social Sciences, Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5082-4161","authenticated-orcid":false,"given":"Ari A.","family":"Mennander","sequence":"additional","affiliation":[{"name":"Department of Cardio\u2010Thoracic Surgery Tays Heart Hospital, Tampere University Hospital  Tampere Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4286-933X","authenticated-orcid":false,"given":"Kati M.","family":"J\u00e4rvel\u00e4","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anesthesia and Intensive Care Tays Heart Hospital, Tampere University Hospital  Tampere Finland"},{"name":"Faculty of Medicine and Health Technology, Tampere University  Tampere 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