{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:27:16Z","timestamp":1784039236253,"version":"3.55.0"},"reference-count":45,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T00:00:00Z","timestamp":1416096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T00:00:00Z","timestamp":1416096000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"NIH, NCI","award":["P30CA006927"],"award-info":[{"award-number":["P30CA006927"]}]},{"name":"NIH, NIA","award":["R01AG048602"],"award-info":[{"award-number":["R01AG048602"]}]},{"name":"NIH, NIAID","award":["R01AI065544"],"award-info":[{"award-number":["R01AI065544"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging Cell"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1111\/acel.12291","type":"journal-article","created":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T03:57:13Z","timestamp":1416196633000},"page":"180-190","source":"Crossref","is-referenced-by-count":38,"title":["The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by<scp>IL<\/scp>\u201015\/<scp>IL<\/scp>\u201015R\u03b1 treatment"],"prefix":"10.1111","volume":"14","author":[{"given":"Savita","family":"Nair","sequence":"first","affiliation":[{"name":"Immune Cell Development and Host Defense Program The Research Institute at Fox Chase Cancer Center 333 Cottman Avenue Philadelphia PA 19111 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Fang","sequence":"additional","affiliation":[{"name":"Immune Cell Development and Host Defense Program The Research Institute at Fox Chase Cancer Center 333 Cottman Avenue Philadelphia PA 19111 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis J.","family":"Sigal","sequence":"additional","affiliation":[{"name":"Immune Cell Development and Host Defense Program The Research Institute at Fox Chase Cancer Center 333 Cottman Avenue Philadelphia PA 19111 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.20.6371"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.3.1141"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2013.11.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.52.1.119-128.1984"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.12.7511"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2012.04.005"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1301625"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1088"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2012.06.001"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1318281111"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131560"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.69.9.5875-5877.1995"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.4.2099"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1012128107"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0040030"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20100282"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.02.015"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.10.7086"},{"key":"e_1_2_9_20_1","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.4049\/jimmunol.149.6.1957","article-title":"Genomic structure and strain\u2010specific expression of the natural killer cell receptor NKR\u2010P1","volume":"149","author":"Giorda R","year":"1992","journal-title":"J. Immunol."},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.11.016"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.3.1517"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2012.00839.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc727"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.8.4764"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.191.5.771"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni796"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2005.05.012"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.23.021704.115526"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2006.10.007"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2010.08.009"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80664-0"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.1.661-667.2005"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2013.00450"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200940056"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2012.04.009"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2008.01.003"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(02)00038-2"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI66381"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0600240103"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.01659"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2012.04.008"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.9.6072"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3044"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.190.12.1801"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041270307"}],"container-title":["Aging Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facel.12291","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acel.12291","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acel.12291","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/acel.12291\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T06:37:48Z","timestamp":1689662268000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.12291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,16]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/acel.12291"],"URL":"https:\/\/doi.org\/10.1111\/acel.12291","archive":["Portico"],"relation":{},"ISSN":["1474-9718","1474-9726"],"issn-type":[{"value":"1474-9718","type":"print"},{"value":"1474-9726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,16]]}}}