{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:01:42Z","timestamp":1790632902060,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30770882"],"award-info":[{"award-number":["30770882"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470519"],"award-info":[{"award-number":["81470519"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31400998"],"award-info":[{"award-number":["31400998"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91439203"],"award-info":[{"award-number":["91439203"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31130031"],"award-info":[{"award-number":["31130031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging Cell"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1111\/acel.12460","type":"journal-article","created":{"date-parts":[[2016,5,2]],"date-time":"2016-05-02T04:10:44Z","timestamp":1462162244000},"page":"625-633","source":"Crossref","is-referenced-by-count":67,"title":["Deregulation of\n            <scp>XBP<\/scp>\n            1 expression contributes to myocardial vascular endothelial growth factor\u2010A expression and angiogenesis during cardiac hypertrophy\n            <i>in\u00a0vivo<\/i>"],"prefix":"10.1111","volume":"15","author":[{"given":"Quanlu","family":"Duan","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Ni","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peihua","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Gong","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhejun","family":"Cai","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Hui","family":"Zou","sequence":"additional","affiliation":[{"name":"Center for Molecular and Translational Medicine Georgia State University Atlanta 30303 GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dao Wen","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department Internal Medicine, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030 People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13119"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-015-0725-4"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.24942"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2009.10.011"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009575"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.091415198"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.119388"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.227033"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000051865.66123.B7"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1983"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2006.03.014"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000215207.54689.31"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-4173"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.5.7.2973"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00478.2007"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1158042"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2449"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811371106"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.412783"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1857"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1998.0714"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055155"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2005.11.008"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI18213"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000137836.95625.D4"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103160"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2099"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012521"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-1606"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1593\/tlo.08211"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M411275200"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2012.11.016"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05602"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2010.02.004"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvq267"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60894-5"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI24682"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2012.09.004"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.783852"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000233317.70421.03"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(90)90620-5"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2282"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.01.014"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.2337\/db13-1665"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00611-0"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0903197106"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.001337"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2293"}],"container-title":["Aging Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facel.12460","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acel.12460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acel.12460","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/acel.12460\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T17:06:28Z","timestamp":1625504788000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.12460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1111\/acel.12460"],"URL":"https:\/\/doi.org\/10.1111\/acel.12460","archive":["Portico"],"relation":{},"ISSN":["1474-9718","1474-9726"],"issn-type":[{"value":"1474-9718","type":"print"},{"value":"1474-9726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5]]}}}