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Religious and existential variables may play an important role in the health impacts of bereavement. Theorized pathways linking religious and existential variables with health have suggested these associations are due to intermediary psychosocial variables, but have not been tested in bereavement. This research empirically tested these pathways in a bereaved population. In <jats:italic>N<\/jats:italic>\u2009=\u200973 adults within 1\u2009year of bereavement (mean age\u2009=\u200964.36), this study examined associations between (1) <jats:italic>religious and existential characteristics<\/jats:italic> (religious and spiritual struggles, intrinsic religiosity, and existential quest) and <jats:italic>intermediary psychosocial variables<\/jats:italic> (depression, loneliness, and difficulties in emotion regulation), and between (2) <jats:italic>intermediary psychosocial variables<\/jats:italic> and <jats:italic>bereavement\u2010relevant health outcomes<\/jats:italic> (self\u2010reported health, change in health since last year, grief severity, and cardiovascular biomarkers). Cardiovascular biomarkers (heart rate, heart rate variability, and blood pressure) were collected before, during, and after a laboratory grief recall emotion elicitation. Anticipated associations between self\u2010reported <jats:italic>religious and existential characteristics<\/jats:italic> and <jats:italic>intermediary variables,<\/jats:italic> and between <jats:italic>intermediary variables<\/jats:italic>\u00a0and self\u2010reported bereavement\u2010relevant outcomes, were consistently observed. However, associations between <jats:italic>intermediary variables<\/jats:italic> and cardiovascular biomarkers were largely unobserved. This study examined the role of religious and existential variables in whole\u2010person health after bereavement and is among the first to include biomarkers of cardiovascular risk. Results suggest that although religious and existential variables are associated with important bereavement\u2010related outcomes, these associations may be \u201cskin\u2010deep,\u201d and extensions to cardiovascular functioning should be re\u2010examined.<\/jats:p>","DOI":"10.1111\/acel.14014","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:25:10Z","timestamp":1697441110000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Associations of religious and existential variables with psychosocial factors and biomarkers of cardiovascular risk in bereavement"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0415-6411","authenticated-orcid":false,"given":"Roman","family":"Palitsky","sequence":"first","affiliation":[{"name":"Department of Psychology University of Arizona  Tucson Arizona USA"},{"name":"Emory University Spiritual Health, Woodruff 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