{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:13:10Z","timestamp":1791396790243,"version":"4.3.3"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,1,13]],"date-time":"2013-01-13T00:00:00Z","timestamp":1358035200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2013,1]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n \n The goal of this study was to determine the association of first pass success with the incidence of adverse events (\n AE<\/jats:styled-content>\n s) during emergency department (\n ED<\/jats:styled-content>\n ) intubations.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This was a retrospective analysis of prospectively collected continuous quality improvement data based on orotracheal intubations performed in an academic\n ED<\/jats:styled-content>\n over a 4\u2010year period. Following each intubation, the operator completed a data form regarding multiple aspects of the intubation, including patient and operator characteristics, method of intubation, device used, the number of attempts required, and\n AE<\/jats:styled-content>\n s. Numerous\n AE<\/jats:styled-content>\n s were tracked and included events such as witnessed aspiration, oxygen desaturation, esophageal intubation, hypotension, dysrhythmia, and cardiac arrest. Multivariable logistic regression was used to assess the relationship between the primary predictor variable of interest, first pass success, and the outcome variable, the presence of one or more\n AE<\/jats:styled-content>\n s, after controlling for various other potential risk factors and confounders.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Over the 4\u2010year study period, there were 1,828 orotracheal intubations. If the intubation was successful on the first attempt, the incidence of one or more AEs was 14.2% (95% confidence interval [CI]\u00a0=\u00a012.4% to 16.2%). In cases requiring two attempts, the incidence of one or more AEs was 47.2% (95% CI\u00a0=\u00a041.8% to 52.7%); in cases requiring three attempts, the incidence of one or more AEs was 63.6% (95% CI\u00a0=\u00a053.7% to 72.6%); and in cases requiring four or more attempts, the incidence of one or more AEs was 70.6% (95% CI\u00a0=\u00a056.2.3% to 82.5%). Multivariable logistic regression showed that more than one attempt at tracheal intubation was a significant predictor of one or more AEs (adjusted odds ratio [\n aOR<\/jats:styled-content>\n ]\u00a0=\u00a07.52, 95% CI\u00a0=\u00a05.86 to 9.63).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n When performing orotracheal intubation in the\n ED<\/jats:styled-content>\n , first pass success is associated with a relatively small incidence of\n AE<\/jats:styled-content>\n s. As the number of attempts increases, the incidence of\n AE<\/jats:styled-content>\n s increases substantially.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/acem.12055","type":"journal-article","created":{"date-parts":[[2013,1,13]],"date-time":"2013-01-13T20:30:31Z","timestamp":1358109031000},"page":"71-78","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":513,"title":["The Importance of First Pass Success When Performing Orotracheal Intubation in the Emergency Department"],"prefix":"10.1111","volume":"20","author":[{"given":"John C.","family":"Sakles","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine University of Arizona (JCS, JM, CW, US) Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Chiu","sequence":"additional","affiliation":[{"name":"University of Arizona College of Medicine (SC) Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarrod","family":"Mosier","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Arizona (JCS, JM, CW, US) Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrine","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Arizona (JCS, JM, CW, US) Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Stolz","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Arizona (JCS, JM, CW, US) Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318201c415"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000122825.04923.15"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2004.01.007"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199502000-00007"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.1999.tb00091.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200305000-00032"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2012.04.005"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2008.12.019"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2004.05.006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2005.01.009"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2010.02.024"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31818ddb90"}],"container-title":["Academic Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facem.12055","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.12055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T05:39:27Z","timestamp":1698644367000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acem.12055"}},"subtitle":[],"editor":[{"given":"Robert F.","family":"Reardon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/acem.12055"],"URL":"https:\/\/doi.org\/10.1111\/acem.12055","archive":["Portico"],"relation":{},"ISSN":["1069-6563","1553-2712"],"issn-type":[{"value":"1069-6563","type":"print"},{"value":"1553-2712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"2012-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-07-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}