{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:57:31Z","timestamp":1788872251745,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T00:00:00Z","timestamp":1422489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Fred Lovejoy Resident Research Award"},{"DOI":"10.13039\/100006823","name":"Boston Children's Hospital","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006823","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2015,2]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n \n The authors measured the effect of a traumatic or unsuccessful lumbar puncture (\n LP<\/jats:styled-content>\n ) on the management of febrile infants.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This was a 10\u2010year retrospective cross\u2010sectional study of low\u2010risk infants by the \u201cBoston\u201d criteria 28 to 60\u00a0days of age presenting to the emergency department for evaluation of fever. \u201cNormal\n LP<\/jats:styled-content>\n \u201d infants had cerebrospinal fluid (\n CSF<\/jats:styled-content>\n )\n WBC<\/jats:styled-content>\n < 10\u00a0\u00d7\u00a010\n 6<\/jats:sup>\n cells\/L. \u201cTraumatic\u201d or \u201cunsuccessful\n LP<\/jats:styled-content>\n \u201d infants had\n CSF<\/jats:styled-content>\n red blood cell count \u2265 10\u00a0\u00d7\u00a010\n 9<\/jats:sup>\n cells\/L or no\n CSF<\/jats:styled-content>\n cell counts obtained, respectively. A serious bacterial infection (\n SBI<\/jats:styled-content>\n ) was defined as growth of a bacterial pathogen from culture. The hospitalization and\n SBI<\/jats:styled-content>\n rates were compared between infants with normal versus traumatic or unsuccessful\n LP<\/jats:styled-content>\n s.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of the 929 study infants, 756 (81.4%) had normal\n LP<\/jats:styled-content>\n s, and 173 (18.6%) had traumatic or unsuccessful\n LP<\/jats:styled-content>\n s. Infants with traumatic or unsuccessful\n LP<\/jats:styled-content>\n s had a higher hospitalization rate (72.3% traumatic or unsuccessful\n LP<\/jats:styled-content>\n vs. 18.1% normal\n LP<\/jats:styled-content>\n ; difference\u00a0= 54.1%; 95% confidence interval [\n CI<\/jats:styled-content>\n ] = 46.4% to 60.8%), but a similar\n SBI<\/jats:styled-content>\n rate (2.9% vs. 4.1%; difference\u00a0= 1.2%; 95%\n CI<\/jats:styled-content>\n = \u20132.7% to 3.6%). No infant had proven bacterial meningitis (0% risk, 95%\n CI<\/jats:styled-content>\n = 0 to 0.3%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Low\u2010risk infants aged 28 to 60\u00a0days with traumatic or unsuccessful\n LP<\/jats:styled-content>\n s are more frequently hospitalized, although\n SBI<\/jats:styled-content>\n rates were similar to those of infants with normal\n LP<\/jats:styled-content>\n s.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/acem.12582","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T19:42:51Z","timestamp":1422560571000},"page":"240-243","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["The Effect of Traumatic Lumbar Puncture on Hospitalization Rate for Febrile Infants 28 to 60 Days of Age"],"prefix":"10.1111","volume":"22","author":[{"given":"Elizabeth W.","family":"Pingree","sequence":"first","affiliation":[{"name":"Department of Medicine Boston Children's Hospital Boston MA"},{"name":"Division of General Pediatrics Boston Children's Hospital Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir A.","family":"Kimia","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Boston Children's Hospital Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise E.","family":"Nigrovic","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Boston Children's Hospital Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.103.3.627"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2006.10.018"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.5.1169"},{"key":"e_1_2_7_5_1","unstructured":"United States Department of Labor Bureau of Labor Statistics.Consumer Price Index. Available at:http:\/\/www.bls.gov\/cpi\/. Accessed Nov 8 2014."},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80591-8"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-0479"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2008.00117.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0519"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1542\/peds.111.3.525","article-title":"Interpretation of traumatic lumbar punctures: who can go home?","volume":"111","author":"Mazor SS","year":"2003","journal-title":"Pediatrics"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1005384"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e31828a2011"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SIH.0b013e318216bfc1"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-0607"}],"container-title":["Academic Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facem.12582","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.12582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T07:51:27Z","timestamp":1696492287000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acem.12582"}},"subtitle":[],"editor":[{"given":"Elizabeth","family":"Alpern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,1,29]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1111\/acem.12582"],"URL":"https:\/\/doi.org\/10.1111\/acem.12582","archive":["Portico"],"relation":{},"ISSN":["1069-6563","1553-2712"],"issn-type":[{"value":"1069-6563","type":"print"},{"value":"1553-2712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,29]]},"assertion":[{"value":"2014-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-09-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-01-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}