{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:30:56Z","timestamp":1789500656062,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T00:00:00Z","timestamp":1440028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective was to determine the frequency of postreduction, hospital\u2010level interventions among children with successful reduction of ileocolic intussusception and identify factors that predict the need for such interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective cross\u2010sectional study of children who underwent successful enema reduction for ileocolic intussusception at a single emergency department. Hospital\u2010level interventions were included if they occurred within 24\u00a0hours of reduction and were further classified as either major (recurrence or possible perforation) or minor (imaging for suspected recurrence or administration of parenteral narcotics or antiemetics). Binary logistic regression was used to identify predictors for hospital\u2010level interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 464 children underwent enema reduction. The median age was 1.7\u00a0years (interquartile range [<jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>]\u00a0=\u00a00.8 to 2.5\u00a0years), and 66% were male. A total of 435 (94%) were hospitalized with a median hospital stay of 25\u00a0hours (<jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\u00a0=\u00a019 to 34\u00a0hours). Nineteen percent (95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]\u00a0=\u00a015% to 22%) needed postreduction interventions, including 6% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\u00a0=\u00a04% to 9%) who required major interventions. The median time to any hospital intervention was 9.9\u00a0hours (<jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\u00a0=\u00a06.3 to 16.4\u00a0hours). We identified two independent predictors for hospital\u2010level interventions: duration of symptoms\u00a0&gt;\u00a024\u00a0hours (adjusted odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>]\u00a0=\u00a02.1, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\u00a0=\u00a01.3 to 3.4) and location of the intussusception tip at (or proximal to) the hepatic flexure (adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a01.9, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\u00a0=\u00a01.1 to 3.3); the latter factor was also a predictor of a major intervention. None of the children (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\u00a0=\u00a00 to 1.0%) had an acute decompensation after an initially successful enema reduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Clinical decompensation is rare and recurrence is relatively low after an uncomplicated reduction of ileocolic intussusception. However, one in five children required hospital\u2010level interventions after reduction. Children with the intussusception tip at (or proximal to) the hepatic flexure, and those with symptoms for longer than 24\u00a0hours, are more likely to require subsequent interventions. Although outpatient management appears safe after a period of observation, caregivers should be counseled about the risk of ongoing symptoms and recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acem.12741","type":"journal-article","created":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T19:55:03Z","timestamp":1440100503000},"page":"1042-1047","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Frequency of Postreduction Interventions After Successful Enema Reduction of Intussusception"],"prefix":"10.1111","volume":"22","author":[{"given":"Elisabeth M.","family":"Lessenich","sequence":"first","affiliation":[{"name":"Harvard Affiliated Emergency Medicine Residency Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir A.","family":"Kimia","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Medicine Children's Hospital Boston Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Mandeville","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Medicine Children's Hospital Boston Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Medicine Children's Hospital Boston Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assaf","family":"Landschaft","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Medicine Children's Hospital Boston Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Radiology Children's Hospital Boston Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard 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