{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:42:55Z","timestamp":1787013775433,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T00:00:00Z","timestamp":1477872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objective of this study was to determine if physicians would alter their prescribing preferences after sampling liquid formulations of medications for common pediatric diagnoses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a prospective interventional before\/after study conducted at an academic medical center in the United States. The participants of interest included emergency, family medicine, and pediatric physicians. Participants initially completed a brief survey for their primary oral liquid medication of choice for the treatment of selected disease states. These included otitis media, sinusitis, cellulitis, asthma, colitis, and pneumonia. Participants were asked to choose one of the medication options for each disease and then were given all medications to sample for a taste test. The prescribing preference survey was then repeated. The primary outcome was change in prescribing. McNemar's test was used to evaluate change in proportion of medications chosen before and after taste testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 101 physicians who participated in the study. There were three conditions for which participants changed their prescribing preferences significantly. These were otitis media (change from amoxicillin to cefdinir, difference = 13.2%, 95% confidence interval [\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ] = 5.5% to 21.0%), asthma exacerbation (change from dexamethasone or prednisone to prednisolone, 28%, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 15.9% to 40.1%), and pneumonia (change from azithromycin to amoxicillin, 16.0%, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 6.4% to 25.6%). There was no significant change with respect to the other scenarios.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Physicians showed preferences for certain pediatric medications based on taste and showed significant changes in prescribing preferences for some common pediatric diagnoses after tasting different medications for these conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acem.13020","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T04:17:27Z","timestamp":1465186647000},"page":"1243-1247","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Medication Palatability Affects Physician Prescribing Preferences for Common Pediatric Conditions"],"prefix":"10.1111","volume":"23","author":[{"given":"Hans","family":"Bradshaw","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine College of Medicine University of Arizona Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine College of Medicine University of Arizona Tucson AZ"},{"name":"Department of Emergency Medicine Tucson Medical Center Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Services Banner\u2010University Medical Center Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Stolz","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine College of Medicine University of Arizona Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oday","family":"Naser","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine College of Medicine University of Arizona Tucson AZ"},{"name":"Emergency Department Oroville Hospital Oroville CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Peck","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice &amp; Science College of Pharmacy University of Arizona Tucson AZ"},{"name":"Department of Pharmacy Memorial Katy Hospital Katy TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad E.","family":"Patanwala","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice &amp; Science College of Pharmacy University of Arizona Tucson AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-2879"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2011-300909"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200101000-00001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2165\/00148581-200709050-00001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1998.tb126802.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2014.04.069"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-3488"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir531"},{"key":"e_1_2_7_10_1","first-page":"CD003539","article-title":"Interventions to improve antibiotic prescribing practices in ambulatory care","volume":"4","author":"Arnold SR","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.154.3.267"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2011.08.003"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2011.01330.x"}],"container-title":["Academic Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facem.13020","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.13020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:41:49Z","timestamp":1695688909000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acem.13020"}},"subtitle":[],"editor":[{"given":"Mark R.","family":"Zonfrillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,10,31]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/acem.13020"],"URL":"https:\/\/doi.org\/10.1111\/acem.13020","archive":["Portico"],"relation":{},"ISSN":["1069-6563","1553-2712"],"issn-type":[{"value":"1069-6563","type":"print"},{"value":"1553-2712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,31]]},"assertion":[{"value":"2016-04-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-05-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}