{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:14:36Z","timestamp":1777436076334,"version":"3.51.4"},"reference-count":51,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,10,25]],"date-time":"2018-10-25T00:00:00Z","timestamp":1540425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004072","name":"R Baby Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010506","name":"Indiana University Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010506","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Pediatric out\u2010of\u2010hospital cardiac arrest survival outcomes are dismal (&lt;10%). Care that is provided in adherence to established guidelines has been associated with improved survival. Lower mortality rates have been reported in higher\u2010volume hospitals, teaching hospitals, and trauma centers. The primary objective of this article was to explore the relationship of hospital characteristics, such as annual pediatric patient volume, to adherence to pediatric cardiac arrest guidelines during an in\u00a0situ simulation. Secondary objectives included comparing adherence to other team, provider, and system factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective, multicenter, observational study evaluated interprofessional teams in their native emergency department (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>) resuscitation bays caring for a simulated 5\u2010year\u2010old child presenting in cardiac arrest. The primary outcome, adherence to the American Heart Association pediatric guidelines, was assessed using a 14\u2010item tool including three component domains: basic life support (<jats:styled-content style=\"fixed-case\">BLS<\/jats:styled-content>), pulseless electrical activity (<jats:styled-content style=\"fixed-case\">PEA<\/jats:styled-content>), and ventricular fibrillation (<jats:styled-content style=\"fixed-case\">VF<\/jats:styled-content>). Provider, team, and hospital\u2010level data were collected as independent data. <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s were evaluated in four pediatric volume groups (low\u00a0&lt;\u00a01,800\/year; medium 1,800\u20134,999; medium\u2010high 5,000\u20139,999; high\u00a0&gt;\u00a010,000). Cardiac arrest adherence and domains were evaluated by pediatric patient volume and other team and hospital\u2010level characteristics, and path analyses were performed to evaluate the contribution of patient volume, systems readiness, and teamwork on <jats:styled-content style=\"fixed-case\">BLS<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> PEA<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">VF<\/jats:styled-content> adherence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 101 teams from a spectrum of 50 <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s participated including nine low pediatric volume (&lt;1,800\/year), 36 medium volume (1,800\u20134,999\/year), 24 medium\u2010high (5,000\u20139,999\/year), and 32 high volume (\u226510000\/year). The median total adherence score was 57.1 (interquartile range\u00a0= 50.0\u201378.6). This was not significantly different across the four volume groups. The highest level of adherence for <jats:styled-content style=\"fixed-case\">BLS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PEA<\/jats:styled-content> domains was noted in the medium\u2010high\u2013volume sites, while no difference was noted for the <jats:styled-content style=\"fixed-case\">VF<\/jats:styled-content> domain. The lowest level of <jats:styled-content style=\"fixed-case\">BLS<\/jats:styled-content> adherence was noted in the lowest\u2010volume <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s. Improved adherence was not directly associated with higher pediatric readiness survey (<jats:styled-content style=\"fixed-case\">PRS<\/jats:styled-content>) score provider experience, simulation teamwork performance, or more providers with Pediatric Advanced Life Support (<jats:styled-content style=\"fixed-case\">PALS<\/jats:styled-content>) training. <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s in teaching hospitals with a trauma center designation that served only children demonstrated higher adherence compared to nonteaching hospitals (64.3 vs 57.1), nontrauma centers (64.3 vs. 57.1), and mixed pediatric and adult departments (67.9 vs. 57.1), respectively. The overall effect sizes for total cardiac adherence score are <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> type \u03b3\u00a0=\u00a00.47 and pediatric volume (low and medium vs. medium\u2010high and high) \u03b3\u00a0=\u00a00.41. A series of path analyses models was conducted that indicated that overall pediatric <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> volume predicted significantly better guideline adherence, but the effect of volume on performance was only mediated by the <jats:styled-content style=\"fixed-case\">PRS<\/jats:styled-content> for the <jats:styled-content style=\"fixed-case\">VF<\/jats:styled-content> domain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrated variable adherence to pediatric cardiac arrest guidelines across a spectrum of <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s. Overall adherence was not associated with <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> pediatric volume. Medium\u2010high\u2013volume <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s demonstrated the highest levels of adherence for <jats:styled-content style=\"fixed-case\">BLS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PEA<\/jats:styled-content>. Lower\u2010volume <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s were noted to have lower adherence to <jats:styled-content style=\"fixed-case\">BLS<\/jats:styled-content> guidelines. Improved adherence was not directly associated with higher <jats:styled-content style=\"fixed-case\">PRS<\/jats:styled-content> score provider experience, simulation teamwork performance, or more providers with <jats:styled-content style=\"fixed-case\">PALS<\/jats:styled-content> training. This study demonstrates that current approaches optimizing the care of children in cardiac arrest in the <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> (provider training, teamwork training, environmental preparation) are insufficient.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acem.13564","type":"journal-article","created":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T11:12:57Z","timestamp":1536405177000},"page":"1396-1408","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Adherence to Pediatric Cardiac Arrest Guidelines Across a Spectrum of Fifty Emergency Departments: A Prospective, In Situ, Simulation\u2010based Study"],"prefix":"10.1111","volume":"25","author":[{"given":"Marc","family":"Auerbach","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Emergency Medicine Yale University School of Medicine New Haven CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Alpert School of Medicine at Brown University Providence RI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis","family":"Whitfill","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Emergency Medicine Yale University School of Medicine New Haven CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janette","family":"Baird","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Alpert School of Medicine at Brown University Providence RI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal","family":"Abulebda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Critical Care Indiana University School of Medicine Riley Hospital for Children at Indiana University Health Indianapolis IN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ambika","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Emergency Medicine Yale University School of Medicine New Haven CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riad","family":"Lutfi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Critical Care Indiana University School of Medicine Riley Hospital for Children at Indiana University Health Indianapolis IN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcie","family":"Gawel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Emergency Medicine Yale University School of Medicine New Haven CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Emergency Medicine Boston University Boston MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khoon-Yen","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Emergency Medicine University of Pennsylvania Perelman School of Medicine The Children's Hospital of Philadelphia Philadelphia PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Lavoie","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Emergency Medicine University of Pennsylvania Perelman School of Medicine The Children's Hospital of Philadelphia Philadelphia PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinay","family":"Nadkarni","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine University of Pennsylvania Perelman School of Medicine The Children's Hospital of Philadelphia Philadelphia PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Dudas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of General Pediatrics and Adolescent Medicine Johns Hopkins University School of Medicine Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Kessler","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center New York NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Katznelson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Emergency Medicine Johns Hopkins University School of Medicine Baltimore MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Ganghadaran","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine and Pediatrics Children's Hospital at Montefiore Bronx NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda Fiedor","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine and Pediatrics Children's Hospital of Pittsburgh University of Pittsburgh Medical Center Pittsburgh PA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.054"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.802678"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2005.05.028"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000441139.02102.80"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-14-0082"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31829763e2"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.157"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.138"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-2741"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2012.07.032"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.07.016"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2012.10.013"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2014.06.008"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1865-1380-6-13"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2018.04.019"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.10.074"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.04.022"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.852202"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.059535"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.05.007"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2008.03.513"},{"key":"e_1_2_8_23_1","unstructured":"American Heart Association.Resuscitation Patient Management Tool.2014.http:\/\/www.heart.org\/idc\/groups\/heart-public\/@private\/@wcm\/@hcm\/@gwtg\/documents\/downloadable\/ucm_457481.pdf. Accessed Apr 2 2018."},{"key":"e_1_2_8_24_1","unstructured":"American Heart Association.Resuscitation Fact Sheet.2017.http:\/\/www.heart.org\/idc\/groups\/heart-public\/@private\/@wcm\/@hcm\/@gwtg\/documents\/downloadable\/ucm_434082.pdf. Accessed mmm dd yyyy."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.21.2375"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.3.299"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S129728"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000000297"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2012.01354.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1197\/j.aem.2006.01.023"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1553-7250(10)36034-X"},{"issue":"3","key":"e_1_2_8_32_1","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1097\/SIH.0000000000000269","article-title":"Building a community of practice for researchers: the International Network for Simulation\u2010Based Pediatric Innovation, Research and Education","volume":"13","author":"Cheng A","year":"2018","journal-title":"Simul Healthc"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2010.08.028"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddg247"},{"key":"e_1_2_8_35_1","unstructured":"AppleI.Counter+. Available at:https:\/\/itunes.apple.com\/us\/app\/counter-+\/id478557426?mt=8. Accessed July 14 2015."},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.174"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.12.012"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2009.08.010"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.51.6.1173"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.2307\/270723"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.014016"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2006.05.011"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2009.04.021"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3181e91271"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0131"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2010.07.012"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2006.12.017"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2008.02.007"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2012.02.027"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31829d8654"},{"key":"e_1_2_8_51_1","first-page":"22","article-title":"Effects of practice on competency in single\u2010rescuer cardiopulmonary resuscitation","volume":"23","author":"Oermann MH","year":"2014","journal-title":"Medsurg Nurs"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2105"}],"container-title":["Academic Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.13564","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acem.13564","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.13564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T19:00:37Z","timestamp":1694631637000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acem.13564"}},"subtitle":[],"editor":[{"given":"Rakesh D.","family":"Mistry","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,10,25]]},"references-count":51,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/acem.13564"],"URL":"https:\/\/doi.org\/10.1111\/acem.13564","archive":["Portico"],"relation":{},"ISSN":["1069-6563","1553-2712"],"issn-type":[{"value":"1069-6563","type":"print"},{"value":"1553-2712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,25]]},"assertion":[{"value":"2018-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}