{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:53:58Z","timestamp":1787068438500,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006578","name":"Chi Mei Medical Center","doi-asserted-by":"publisher","award":["11001 Physician\u2010Scientist"],"award-info":[{"award-number":["11001 Physician\u2010Scientist"]}],"id":[{"id":"10.13039\/501100006578","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006578","name":"Chi Mei Medical Center","doi-asserted-by":"publisher","award":["111CM\u2010TMU\u201016"],"award-info":[{"award-number":["111CM\u2010TMU\u201016"]}],"id":[{"id":"10.13039\/501100006578","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Artificial intelligence (AI) prediction is increasingly used for decision making in health care, but its application for adverse outcomes in emergency department (ED) patients with acute pancreatitis (AP) is not well understood. This study aimed to clarify this aspect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 8274 ED patients with AP in three hospitals from 2009 to 2018 were analyzed. Demographic data, comorbidities, laboratory results, and adverse outcomes were included. Six algorithms were evaluated, and the one with the highest area under the curve (AUC) was implemented into the hospital information system (HIS) for real\u2010time prediction. Predictive accuracy was compared between the AI model and Bedside Index for Severity in Acute Pancreatitis (BISAP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean\u2009\u00b1\u2009SD age was 56.1\u2009\u00b1\u200916.7\u2009years, with 67.7% being male. The AI model was successfully implemented in the HIS, with Light Gradient Boosting Machine (LightGBM) showing the highest AUC for sepsis (AUC 0.961) and intensive care unit (ICU) admission (AUC 0.973), and eXtreme Gradient Boosting (XGBoost) showing the highest AUC for mortality (AUC 0.975). Compared to BISAP, the AI model had superior AUC for sepsis (BISAP 0.785), ICU admission (BISAP 0.778), and mortality (BISAP 0.817).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The first real\u2010time AI prediction model implemented in the HIS for predicting adverse outcomes in ED patients with AP shows favorable initial results. However, further external validation is needed to ensure its reliability and accuracy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acem.14824","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T00:34:48Z","timestamp":1698366888000},"page":"149-155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Real\u2010time artificial intelligence predicts adverse outcomes in acute pancreatitis in the emergency department: Comparison with clinical decision rule"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3937-4221","authenticated-orcid":false,"given":"Ching\u2010Hung","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Jung","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Information Systems Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Shan","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Medical Research Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Ting","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Medical Research Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010I","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Medical Research Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-0152","authenticated-orcid":false,"given":"Chien\u2010Chin","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Chi Mei Medical Center  Tainan Taiwan"},{"name":"School of Medicine, College of Medicine National Sun Yat\u2010Sen University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung\u2010Jung","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Chi Mei Medical Center  Tainan Taiwan"},{"name":"School of Medicine, College of Medicine National Sun Yat\u2010Sen University  Kaohsiung Taiwan"},{"name":"Department of Emergency Medicine Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhih\u2010Cherng","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine National Sun Yat\u2010Sen University  Kaohsiung Taiwan"},{"name":"Division of Cardiology, Department of Internal Medicine Chi Mei Medical Center  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3595-2952","authenticated-orcid":false,"given":"Chien\u2010Cheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Chi Mei Medical Center  Tainan Taiwan"},{"name":"School of Medicine, College of Medicine National Sun Yat\u2010Sen University  Kaohsiung Taiwan"},{"name":"Department of Emergency Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Department of Environmental and Occupational Health, College of Medicine National Cheng Kung University  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medical Research Chi Mei Medical Center  Tainan 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Vol 2023: Chi Mei Medical Center.2023."},{"key":"e_1_2_10_17_1","unstructured":"HuangCC.AI in the ED. Vol 20222021."},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/20009666.2017.1361292"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/bega.2002.0313"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1613\/jair.953"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2023.105176"},{"key":"e_1_2_10_22_1","first-page":"1988","article-title":"Bedside index (BISAP) v\/s Ranson scores in predicting mortality and severity in patients with acute pancreatitis","volume":"71","author":"Kapadia NN","year":"2021","journal-title":"J Pak Med Assoc"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1076-6332(03)80186-1"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000090032"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000327903"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.37107"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.00117"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-93771-y"}],"container-title":["Academic Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.14824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T07:38:56Z","timestamp":1708673936000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acem.14824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,23]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/acem.14824"],"URL":"https:\/\/doi.org\/10.1111\/acem.14824","archive":["Portico"],"relation":{},"ISSN":["1069-6563","1553-2712"],"issn-type":[{"value":"1069-6563","type":"print"},{"value":"1553-2712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,23]]},"assertion":[{"value":"2023-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}