{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T14:51:01Z","timestamp":1782485461626,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009530","name":"Jawaharlal Institute Of Postgraduate Medical Education and Research","doi-asserted-by":"publisher","award":["JIP\/Res\/Intramural\/Phs\u20101\/2023\u201024"],"award-info":[{"award-number":["JIP\/Res\/Intramural\/Phs\u20101\/2023\u201024"]}],"id":[{"id":"10.13039\/501100009530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Study Objective<\/jats:title>\n                    <jats:p>We evaluated the efficacy and safety of ultrasound\u2010guided pericapsular nerve group (PENG) block for initial pain management in adult emergency department (ED) patients with hip fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective, randomized, double\u2010blinded, controlled trial was conducted at a tertiary care academic ED. Adult patients (\u2265\u200918\u2009years) with traumatic hip fractures and Numerical Rating Scale (NRS) pain scores &gt;\u20094 were randomized to ultrasound\u2010guided PENG block with bupivacaine or sham procedure. Both groups received standard intravenous analgesia. The primary outcome was the difference in NRS scores over 3\u2009h. Secondary outcomes included total rescue analgesia (morphine equivalents) and adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 167 screened, 80 patients were enrolled (40 per group). Pain scores were significantly lower in the PENG block group at 30\u2009min (mean difference [MD] \u22123.2; 95% confidence interval [CI]\u20104.2 to \u22122.2), 60\u2009min (MD \u22123.1; 95% CI \u22124.1 to \u22122.1), and 120\u2009min (MD \u22122.0; 95% CI \u22122.6, \u22121.4), compared with sham. Total rescue analgesia was significantly lower in the PENG block group (MD \u22124.6\u2009mg morphine equivalents; 95% CI \u22126.2 to \u22123.1). No significant adverse events were reported, such as hematoma, quadriceps weakness, signs of local anesthetic systemic toxicity (LAST), or significant opioid\u2010related adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In adult ED patients with hip fractures, ultrasound\u2010guided PENG block significantly reduced pain scores and opioid requirements compared with sham, with no significant adverse events reported. PENG block may be an effective, opioid\u2010sparing analgesic strategy for acute hip fractures in the ED.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>Clinical Trial Registry\u2010India: CTRI\/2023\/08\/056595<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acem.70206","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:09:11Z","timestamp":1765598951000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of Ultrasound\u2010Guided\n                    <scp>PENG<\/scp>\n                    Block for Acute Pain Relief in Adult Hip Fracture Patients: A Double\u2010Blind Randomized Trial"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6589-0536","authenticated-orcid":false,"given":"Barath","family":"Vijayan","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine &amp; Trauma Jawaharlal Institute of Postgraduate Medical Education &amp; Research  Puducherry India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2541-5769","authenticated-orcid":false,"given":"S. Manu","family":"Ayyan","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine &amp; Trauma Jawaharlal Institute of Postgraduate Medical Education &amp; Research  Puducherry India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6128-3401","authenticated-orcid":false,"given":"Pasupathy","family":"Palaniappan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Jawaharlal Institute of Postgraduate Medical Education &amp; Research  Puducherry India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4360-588X","authenticated-orcid":false,"given":"Ponnusamy Ramasamy","family":"Pudhiyasamy","sequence":"additional","affiliation":[{"name":"Department of Community Medicine Indira Gandhi Government Medical College  Nagpur Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8489-7473","authenticated-orcid":false,"given":"Swetha","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine &amp; Trauma Jawaharlal Institute of Postgraduate Medical Education &amp; Research  Puducherry India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2325-4719","authenticated-orcid":false,"given":"Anas Mohammed","family":"Muthanikkatt","sequence":"additional","affiliation":[{"name":"Department of Community Medicine Indira Gandhi Government Medical College  Nagpur Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000002465"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/jets.jets_153_24"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0952\u20108180(01)00320\u20108"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0000000000000562"},{"issue":"8","key":"e_1_2_11_6_1","first-page":"859","article-title":"Pericapsular Nerve Group (PENG) Block for Hip Fracture","volume":"43","author":"Gir\u00f3n\u2010Arango L.","year":"2018","journal-title":"Regional Anesthesia and Pain Medicine"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000701"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/XAA.0000000000001320"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2024.04.016"},{"key":"e_1_2_11_10_1","unstructured":"\u201cNMC MD EM CURRICULUM\u2010V6 With Logo Revised\u20101.pdf \u201d(2025) https:\/\/www.nmc.org.in\/wp\u2010content\/uploads\/2024\/10\/NMC%20MD%20EM%20CURRICULUM\u2010V6%20with%20logo%20revised\u20101.pdf."},{"key":"e_1_2_11_11_1","unstructured":"\u201cUse of Invasive Placebos in Research on Local Anaesthetic Interventions\u2014University College London \u201d(2025) https:\/\/ucl.primo.exlibrisgroup.com\/discovery\/fulldisplay?docid=cdi_proquest_journals_846930450&context=PC&vid=44UCL_INST:UCL_VU2&lang=en&adaptor=Primo%20Central&tab=Everything&query=creator equals Fahy %20C AND&mode=advanced&offset=0."},{"key":"e_1_2_11_12_1","unstructured":"\u201cEquianalgesic Chart (Changes in Italics) \u201d(2025) https:\/\/www.healthcare.uiowa.edu\/familymedicine\/fpinfo\/Docs\/adultopioidrefguide.htm."},{"key":"e_1_2_11_13_1","unstructured":"\u201cWhat Is the Opioid Conversion Between Tramadol and Morphine? \u201d(2017) https:\/\/olh.ie\/wp\u2010content\/uploads\/2022\/06\/What\u2010is\u2010the\u2010opioid\u2010conversion\u2010between\u2010tramadol\u2010and\u2010morphine\u2010nov\u201019.pdf."},{"key":"e_1_2_11_14_1","unstructured":"\u201cExcel \u201d(2024) https:\/\/www.microsoft.com\/en\u2010us\/microsoft\u2010365\/excel#:~:text=Microsoft%20Excel%20with%20a%20Microsoft Excel%202007%2C%20and%20Excel%202003."},{"key":"e_1_2_11_15_1","unstructured":"\u201cJamovi \u201d(2025) https:\/\/www.jamovi.org."},{"key":"e_1_2_11_16_1","volume-title":"StatPearls","author":"Emmerson B. 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