{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T07:09:49Z","timestamp":1774422589397,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Older adults are susceptible to adverse drug effects due to age\u2010related changes, a higher prevalence of comorbidities, and complexities in medication management. Nearly half of geriatric patients are prescribed at least one new medication at ED discharge. This study evaluated potential pharmacist interventions on ED discharge prescriptions for older adults using the Geriatric Emergency Medicine Safety Recommendations (GEMS\u2010Rx) list.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center, IRB\u2010approved, retrospective review analyzed ED discharge prescriptions for potentially inappropriate medications based on GEMS\u2010Rx criteria from October 2021 to September 2024 for patients \u2265\u200965\u2009years who were discharged from the ED. Prescriptions were reviewed by a trained pharmacist for medication\u2010related problems (MRPs). Outcomes included: rate of potential pharmacist intervention, number of prescriptions with at least one MRP, MRP types, missing risk vs. benefit documentation, rates of current practice pharmacist review, two or more GEMS\u2010Rx prescriptions at discharge, and polypharmacy. All prescriptions during the study period were reviewed to determine medication sub\u2010class distribution, with a random sample of 250 patients, ensuring at least 10 prescriptions per sub\u2010class, if available. Descriptive statistics were utilized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During the study period, 1458 prescriptions were written for included sub\u2010classes. Of 284 prescriptions screened, 265 (for 250 patients) were included. The median (IQR) age was 69.5 (67\u201375) years with patients on a median (IQR) of 5 (3\u20138) scheduled home medications and discharged with a median (IQR) of 2 (1\u20133) new medications. Skeletal muscle relaxants (37.0%) and first\u2010generation antihistamines (28.7%) were most frequent. Pharmacist intervention was potentially needed in 204 patients (81.6.%) with a median (IQR) of 2 (1, 2) MRPs per patient. Common MRPs included dose adjustment (53.2%), indication mismatch (41.1%), and frequency (38.1%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Most GEMS\u2010Rx prescriptions had at least one MRP, indicating an opportunity for enhanced prescribing. Future research should target strategies to optimize medications at ED discharge for older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acem.70257","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T03:57:28Z","timestamp":1773115048000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Potentially Inappropriate Medications Prescribed to Older Adults Upon Emergency Department Discharge"],"prefix":"10.1111","volume":"33","author":[{"given":"Jessica","family":"Schowe","sequence":"first","affiliation":[{"name":"Department of Pharmacy The Ohio State University Wexner Medical Center  Columbus Ohio USA"},{"name":"Department of Pharmacy Eskenazi Health  Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew M.","family":"North","sequence":"additional","affiliation":[{"name":"Department of Pharmacy The Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyle","family":"Schuchter","sequence":"additional","affiliation":[{"name":"Department of Pharmacy The Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8938-0596","authenticated-orcid":false,"given":"Katherine M.","family":"Hunold","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, College of Medicine The Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Rozycki","sequence":"additional","affiliation":[{"name":"Department of Pharmacy The Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"United States Census Bureau \u201c2023 National Population Projections Tables: Main Series \u201dUpdated February 12 2025 accessed October 22 2025 https:\/\/www.census.gov\/data\/tables\/2023\/demo\/popproj\/2023\u2010summary\u2010tables.html."},{"key":"e_1_2_11_3_1","unstructured":"J. J.Ashman S. M.Schappert andL.Santo \u201cEmergency Department Visits Among Adults Aged 60 and Over: United States 2014\u20132017 Key Findings Data From the National Hospital Ambulatory Medical Care Survey \u201d(2018) accessed August 1 2025 https:\/\/www.cdc.gov\/nchs\/products\/index.htm."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2019.04.007"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.13844"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18372"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2024.01.033"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2012.04.011"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2021.04.054"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90144-C"},{"key":"e_1_2_11_11_1","volume-title":"Geriatric Emergency Department Accreditation (GEDA) Guidelines","author":"American College of Emergency Physicians","year":"2014"},{"key":"e_1_2_11_12_1","article-title":"Interventions to Improve the Appropriate Use of Polypharmacy for Older People","volume":"9","author":"Rankin A.","year":"2018","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2007.12.002"},{"key":"e_1_2_11_14_1","first-page":"1","article-title":"Implementation of Geriatric Clinical Decision Support in the Emergency Department for Potentially Inappropriate Medications","volume":"00","author":"Elder G. A.","year":"2025","journal-title":"Academic Emergency Medicine"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.0814"}],"container-title":["Academic Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.70257","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acem.70257","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acem.70257","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T05:42:25Z","timestamp":1774417345000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acem.70257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/acem.70257"],"URL":"https:\/\/doi.org\/10.1111\/acem.70257","archive":["Portico"],"relation":{},"ISSN":["1069-6563","1553-2712"],"issn-type":[{"value":"1069-6563","type":"print"},{"value":"1553-2712","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70257"}}