{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T07:03:32Z","timestamp":1779865412642,"version":"3.53.1"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["TL1 TR001864"],"award-info":[{"award-number":["TL1 TR001864"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["KL2 TR001862"],"award-info":[{"award-number":["KL2 TR001862"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K76AG094954"],"award-info":[{"award-number":["K76AG094954"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014848","name":"Arnold Ventures","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001146","name":"Greenwall Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001146","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Potentially inappropriate medication prescribing remains a common and preventable source of adverse drug events among older adults, particularly during transitions of care such as ED discharge. We assessed the prevalence and trends of older adults with high\u2010risk medication fills based on the Geriatric Emergency Medication Safety Recommendations (GEMS\u2010Rx) list.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross\u2010sectional study using the 2017\u20132022 Merative\u2122 MarketScan\u00ae Medicare Database. We included ED visits by older adults (65+ years of age) discharged from the ED. The primary outcome was met if a GEMS\u2010Rx medication was filled within 3\u2009days of ED discharge. Multivariable logistic regression estimated associations between patient\u2010 and system\u2010level factors and GEMS\u2010Rx fill after ED discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 616,980 unique ED visits, 58,284 (9.4%; 95% CI: 9.4%\u20139.5%) had a GEMS\u2010Rx medication filled within 3\u2009days of discharge. In 2017, 13,746 (11%) ED encounters resulted in a GEMS\u2010Rx medication fill within 3\u2009days of ED discharge compared to 6,524\u00a0(7%) ED encounters in 2022. Medication fills declined over time, with each additional year associated with a lower odds of GEMS\u2010Rx medication fills. Benzodiazepines (37%), first\u2010generation antihistamines (22%), and skeletal muscle relaxants (11%) were the most frequently filled GEMS\u2010Rx medication classes. Female sex (OR 1.43, 95% CI: 1.41\u20131.46) and younger age (75\u201384\u2009years: OR 0.69, 95% CI: 0.68\u20130.71; \u2265\u200985\u2009years: OR 0.47, 95% CI: 0.46\u20130.48) were associated with higher odds of receiving a GEMS\u2010Rx medication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nearly 1 in 10 older adults filled a high\u2010risk GEMS\u2010Rx medication within 3\u2009days of ED discharge between 2017 and 2022. Despite a decline in GEMS\u2010Rx medication fills over time, younger cohorts of older adults and females were more likely to fill a high\u2010risk medication upon ED discharge. These findings highlight opportunities to continue improving geriatric medication safety through targeted education, decision support, and system\u2010level interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acem.70321","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:21:37Z","timestamp":1778833297000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High\u2010Risk Medication Prescribing Among Older Adults in the Emergency Department: A National Assessment"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3976-7914","authenticated-orcid":false,"given":"Sarah E.","family":"Follman","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Yale School of Medicine  New Haven Connecticut 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K.","family":"Venkatesh","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Yale School of Medicine  New Haven Connecticut USA"},{"name":"Center for Outcomes Research and Evaluation Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reshma","family":"Ramachandran","sequence":"additional","affiliation":[{"name":"Yale Collaboration for Regulatory Rigor, Integrity, and Transparency Yale School of Medicine  New Haven Connecticut USA"},{"name":"Department of Internal Medicine, Section of General Internal Medicine Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6249-1023","authenticated-orcid":false,"given":"Cameron J.","family":"Gettel","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Yale School of Medicine  New Haven Connecticut USA"},{"name":"Center for Outcomes 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