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In the last resort, liver transplantation (LT<\/jats:styled-content>) is considered the only solution to save the patient's life, generating socioeconomic and public health problems. Clinical and sociodemographic characteristics, rejection frequency, and short\u2010 and long\u2010term graft survival are not well known in end\u2010term AC<\/jats:styled-content> patients undergoing LT<\/jats:styled-content>. The aim was to determine the sociodemographic and clinical characteristics, their incidence in LT<\/jats:styled-content>, main pre\u2010 and posttransplant complications, and short\u2010 and long\u2010term post\u2010transplant graft survival in AC<\/jats:styled-content> patients in southeastern S<\/jats:styled-content>pain.<\/jats:p><\/jats:sec>Methods<\/jats:title>The medical records of 1,026 patients who underwent LT<\/jats:styled-content> over the last 23\u00a0years were retrospectively reviewed, and demographic data and posttransplant survivals were analyzed and compared. Biochemical characteristics, major pre\u2010 and posttransplant complications and short\u2010 and long\u2010term survivals were analyzed in a total of 398 male patients with AC undergoing LT<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>AC and viral cirrhosis are the main indications for LT in our study. Mostly represented in our study are AC<\/jats:styled-content> men without associated viral infections with a mean age of 53.06\u00a0years. Main pretransplant complications in AC<\/jats:styled-content> patients are ascites (78.3%) and encephalopathy (43.5%), while acute graft rejection is the most common liver posttransplant complication (26.6%), nevertheless with low graft loss frequency (1.1%). AC<\/jats:styled-content> and autoimmune cirrhosis show the best posttransplant survival in both the short and long term. Patients with AC<\/jats:styled-content> included on the waiting list for LT<\/jats:styled-content> were Child\u2010P<\/jats:styled-content>ugh class B<\/jats:styled-content> (52.1%) and Model for End\u2010Stage Liver Disease score of 10 to 19 (71.2%). The highest percentage of AC<\/jats:styled-content> patient survival was observed at 1\u00a0year posttransplant (81.2%) and progressively decreased over time up to 10\u00a0years posttransplant (69.6%). Pretransplant complications such as ascites and encephalopathy did not have an influence on the percentage of posttransplant survivals, although better survival rates were observed in nonviral AC<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>AC without viral infections is the main indication for LT<\/jats:styled-content> in southeastern S<\/jats:styled-content>pain although its frequency has decreased in last decade. AC<\/jats:styled-content> is a good indication for LT<\/jats:styled-content> for its high survival rate and few posttransplant complications. Despite having a high percentage of pretransplant complications (ascites and encephalopathy) but does not appear to influence survivals being observed posttransplant survival rates above those expected. Conversely, viral infections in the patient with AC<\/jats:styled-content> decrease patient survivals. The main future goals are design new strategies to detect, treat, and reduce AC<\/jats:styled-content> frequency in our population and know alcoholic recidivism rate posttransplant in our population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.13013","type":"journal-article","created":{"date-parts":[[2016,3,25]],"date-time":"2016-03-25T10:54:46Z","timestamp":1458903286000},"page":"794-805","source":"Crossref","is-referenced-by-count":26,"title":["Epidemiology, Evolution, and Long\u2010Term Survival of Alcoholic Cirrhosis Patients Submitted to Liver Transplantation in Southeastern S<\/scp>pain"],"prefix":"10.1111","volume":"40","author":[{"given":"Isabel","family":"Legaz","sequence":"first","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"},{"name":"Department of Legal and Forensic Medicine University of Murcia Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Navarro\u2010Noguera","sequence":"additional","affiliation":[{"name":"Digestive Medicine Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose M.","family":"Bolar\u00edn","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana M.","family":"Garc\u00eda\u2010Alonso","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelio","family":"Luna Maldonado","sequence":"additional","affiliation":[{"name":"Department of Legal and Forensic Medicine University of Murcia Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Mrowiec","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose A.","family":"Campillo","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lourdes","family":"Gimeno","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Moya\u2010Quiles","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria del Rocio","family":"\u00c1lvarez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Minguela Puras","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Miras","sequence":"additional","affiliation":[{"name":"Digestive Medicine Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"S\u00e1nchez\u2010Bueno","sequence":"additional","affiliation":[{"name":"Digestive Medicine Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Muro","sequence":"additional","affiliation":[{"name":"Immunology Service Clinic University Hospital Virgen de la Arrixaca Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2012.04.015"},{"key":"e_1_2_6_3_1","first-page":"102","article-title":"Spectrum of alcoholic liver diseases","volume":"2","author":"Amarapurkar DN","year":"1988","journal-title":"Gastroenterol Today"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510230122"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e3182308b66"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510230513"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5260.1113"},{"key":"e_1_2_6_8_1","unstructured":"2001 ELBA SA Madrid M Bruguera J Rod\u00e9s J Berenguer M Bruguera M Garc\u00eda L Rodrigo Cirrosis hep\u00e1tica compensada. 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