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However, evidence on the directions of these relations is mixed. Longitudinal models of internalizing problem\u2013alcohol use links may identify promising prevention targets. Accordingly, we examined reciprocal associations between anxiety severity and alcohol use, as well as between depression severity and alcohol use, in adolescent girls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were drawn from a population\u2010based longitudinal study of female adolescents. The current sample comprised 2,100 participants (57.1% Black, 42.9% White) assessed annually between ages 13 and 17. Girls self\u2010reported depression severity, anxiety severity, and frequency of alcohol use (consumption of \u22651 full drink) in the past year. Primary caregivers reported on socioeconomic and neighborhood factors; these were included with race, early puberty, and conduct problems (youth\u2010report) as covariates. Anxiety and depression severity were included within a single cross\u2010lagged panel model, along with alcohol use, to isolate their independent and reciprocal links to drinking behavior.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Higher depression severity modestly predicted increased likelihood of subsequent alcohol use from ages 13 to 17. However, inconsistent relations emerged for the reverse pathway: Alcohol use modestly predicted <jats:italic>decreased<\/jats:italic> depression severity at ages 14 and 16; associations were nonsignificant in other lagged associations. Anxiety severity and alcohol use were not consistently associated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Results highlight the key role of depression, relative to anxiety, in predicting later alcohol use. Future studies may examine whether depression prevention programs yield secondary reductions in alcohol use in adolescent girls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.13913","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T07:54:31Z","timestamp":1543218871000},"page":"98-107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Longitudinal Reciprocal Associations Between Anxiety, Depression, and Alcohol Use in Adolescent Girls"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2426-1953","authenticated-orcid":false,"given":"Jessica L.","family":"Schleider","sequence":"first","affiliation":[{"name":"Department of Psychology  Stony Brook University Stony Brook New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Ye","sequence":"additional","affiliation":[{"name":"RAND Corporation  Pittsburgh 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