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Comorbidity among externalizing disorders is commonly investigated at the syndromal and trait level precluding insight into the relationship of symptoms across externalizing disorders. It is unknown whether comorbidity across externalizing disorders holds constant across highly varied, individual alcohol use disorder (<jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content>) criteria. <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria range from symptoms reflecting neuroadaptation (e.g., tolerance) to symptoms reflecting behavioral problems (e.g., social problems). The present study aimed to determine the degree to which individual <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria are associated with symptomatology from other externalizing disorders. Characterization of the degree to which <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria reflect neuroadaptation versus behavioral problems can be used to identify symptom profiles, which, in turn, can be used to inform diagnostic and treatment approaches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 2 large nationally representative samples were used to examine associations between <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria and externalizing behavior. Psychometric inquiries via multivariate and factor analytic approaches estimated relative associations of externalizing behavior and <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria endorsement, as compared to alcohol consumption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our results indicate differential relations of externalizing behavior and <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria endorsement. For example, social problems and role interference criteria were most strongly associated with externalizing behavior across analytic approaches, with general and unique associations with externalizing behavior. Additionally, tolerance was most weakly associated with externalizing behavior across approaches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Results highlight potential etiological heterogeneity among <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content> criteria that could guide future diagnostic refinements and aid in the identification of treatment targets.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.13952","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T06:44:51Z","timestamp":1547016291000},"page":"483-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Are Some Alcohol Use Disorder Criteria More (or Less) Externalizing than Others? 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