{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:24:03Z","timestamp":1790015043749,"version":"4.0.1"},"reference-count":80,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T00:00:00Z","timestamp":1557360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R21AA024926"],"award-info":[{"award-number":["R21AA024926"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["T32AA018108"],"award-info":[{"award-number":["T32AA018108"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcoholism Clin &amp;amp; Exp Res"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Mindfulness\u2010based relapse prevention (\n                      <jats:styled-content style=\"fixed-case\">MBRP<\/jats:styled-content>\n                      ) and transcranial direct current stimulation (\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      ) have independently shown benefits for treating alcohol use disorder (\n                      <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content>\n                      ). Recent work suggests\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      may enhance mindfulness. The combination of\n                      <jats:styled-content style=\"fixed-case\">MBRP<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      may provide synergistic benefits and may target both behavioral and neurobiological dysfunctions in\n                      <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content>\n                      . The goal of this double\u2010blind sham\u2010controlled randomized trial was to examine the efficacy of a rolling group\n                      <jats:styled-content style=\"fixed-case\">MBRP<\/jats:styled-content>\n                      treatment combined with\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      among individuals interested in reducing their drinking.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Individuals who were interested in reducing their alcohol use (\n                      <jats:italic>n\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      84; 40.5% female; mean age\u00a0=\u00a052.3; 98.9% with current\n                      <jats:styled-content style=\"fixed-case\">AUD<\/jats:styled-content>\n                      ) were randomized to receive active (2.0 milliamps) or sham (0.0 milliamps) anodal\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      (5\u00a0cm\u00a0\u00d7\u00a03\u00a0cm electrode) of the right inferior frontal gyrus with the 5\u00a0cm\u00a0\u00d7\u00a03\u00a0cm cathodal electrode applied to the left upper arm, combined with 8\u00a0weeks of outpatient\n                      <jats:styled-content style=\"fixed-case\">MBRP<\/jats:styled-content>\n                      rolling group treatment. Assessments were conducted at baseline, posttreatment, and 2\u00a0months following treatment. The primary outcome was drinks per drinking day, and secondary outcomes were percent heavy drinking days, self\u2010reported craving, alcohol cue reactivity in an alcohol cue task, and response inhibition in a stop signal reaction time task.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Results indicated significant reductions in drinks per drinking day over time,\n                      <jats:italic>B<\/jats:italic>\n                      (\n                      <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>\n                      )\u00a0=\u00a0\u22120.535 (0.16),\n                      <jats:italic>p\u00a0=\u00a0<\/jats:italic>\n                      0.001, and a significant dose effect for number of groups attended,\n                      <jats:italic>B<\/jats:italic>\n                      (\n                      <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>\n                      )\u00a0=\u00a0\u22120.259 (0.11),\n                      <jats:italic>p\u00a0=\u00a0<\/jats:italic>\n                      0.01. There were also significant effects of time and dose for number of groups attended on secondary outcomes of percent heavy drinking days and alcohol cue reactivity. There were no effects of active versus sham\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      on primary or secondary outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Findings from the current study provide initial support for the effectiveness of rolling group\n                      <jats:styled-content style=\"fixed-case\">MBRP<\/jats:styled-content>\n                      as an outpatient treatment for drinking reduction. The current study did not find additive effects of this\n                      <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>\n                      protocol in enhancing\n                      <jats:styled-content style=\"fixed-case\">MBRP<\/jats:styled-content>\n                      among individuals with drinking reduction goals.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.14053","type":"journal-article","created":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T10:49:22Z","timestamp":1555066162000},"page":"1296-1307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Mindfulness\u2010Based Relapse Prevention and Transcranial Direct Current Stimulation to Reduce Heavy Drinking: A Double\u2010Blind Sham\u2010Controlled Randomized Trial"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1086-3067","authenticated-orcid":false,"given":"Katie","family":"Witkiewitz","sequence":"first","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena R.","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria R.","family":"Votaw","sequence":"additional","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam D.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey R.","family":"Roos","sequence":"additional","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stevi J.","family":"Gallegos","sequence":"additional","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent P.","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Psychology University of New Mexico Albuquerque New Mexico"},{"name":"Mind Research Network Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1800-0813","authenticated-orcid":false,"given":"Eric D.","family":"Claus","sequence":"additional","affiliation":[{"name":"Mind Research Network Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2005.08.003"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.17.2003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2016.09.009"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyv066"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2010.07080.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.07.041"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2007.06.011"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2010.06.019"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2011.06.045"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/08897070903250084"},{"key":"e_1_2_6_12_1","unstructured":"2011 Guilford Press New York NY S Bowen N Chawla GA Marlatt Mindfulness\u2010based Relapse Prevention for Addictive Behaviors: A Clinician's Guide"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.4546"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1550059418777404"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2012.10.006"},{"key":"e_1_2_6_16_1","first-page":"1","article-title":"Coordinated, multimodal neuromodulation and neuroimaging","volume":"19","author":"Clark VP","year":"2018","journal-title":"IEEE Intell Inform Bull"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.11.036"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2011.99"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2013.74.141"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.07.083"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajad.12674"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2018.05.002"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-003464"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12463"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2014.12.004"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13171"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsm030"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2009.11.006"},{"key":"e_1_2_6_29_1","unstructured":"2015 American Psychiatric Publishing Inc Arlington VA MB First JBW Williams RL Karg Structured Clinical Interview for DSM\u20105 Disorders Clinical Trials Version"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1999.tb04349.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhy093"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v69n0105"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-014-3504-7"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2007.00378.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2015.0584"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.12205"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/1745691611419671"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2018.e00685"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.07.009"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01198"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00716"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145714000984"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2013.05.024"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2009.110"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2016.09.006"},{"key":"e_1_2_6_46_1","unstructured":"2008 University of Florida Gainesville FL PJ Lang MM Bradley BN Cuthbert International Affective Picture\u00a0System (IAPS): Affective Ratings of Pictures and Instruction Manual. Technical Report A\u20108"},{"key":"e_1_2_6_47_1","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/YCT.0000000000000541","article-title":"tDCS in addiction and impulse control disorders","volume":"34","author":"Lapenta OM","year":"2018","journal-title":"J ECT"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2017.08.005"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2012.03.009"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2017.01.008"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00181"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.12669"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0035230"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.13.1689"},{"key":"e_1_2_6_55_1","unstructured":"2017 Muth\u00e9n & Muth\u00e9n Los Angeles CA LK Muth\u00e9n BO Muth\u00e9n Mplus Users Guide (Version 8)"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2018.08.018"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2012.08.003"},{"key":"e_1_2_6_58_1","unstructured":"2005 National Institutes of Health Bethesda MD National Institute on Alcohol Abuse and Alcoholism Helping Patients Who Drink Too Much: A Clinician's Guide"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(71)90067-4"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1080\/17470919.2017.1397054"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-018-1054-5"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1369-1600.2012.00464.x"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1037\/1082-989X.7.2.147"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2014.00665"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145714000686"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/0376-8716(96)01263-X"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-0357-5_3"},{"key":"e_1_2_6_68_1","first-page":"1183","article-title":"Neuromodulation interventions for addictive disorders: challenges, promise, and roadmap for future research","volume":"140","author":"Spagnolo PA","year":"2017","journal-title":"Brain"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-015-4297-6"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301465"},{"key":"e_1_2_6_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.1989.tb00737.x"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2010.227"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.neuropsych.16080147"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsr076"},{"key":"e_1_2_6_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-016-1541-6"},{"key":"e_1_2_6_76_1","doi-asserted-by":"publisher","DOI":"10.1891\/jcop.2005.19.3.211"},{"key":"e_1_2_6_77_1","doi-asserted-by":"publisher","DOI":"10.1037\/adb0000319"},{"key":"e_1_2_6_78_1","unstructured":"2015 BrainStim 2015 Honolulu HI K Witkiewitz VP Clark Integration of Brain Stimulation and Imaging in Clinical Research and Treatment of Addiction"},{"key":"e_1_2_6_79_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0029258"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.3109\/10826084.2013.856922"},{"key":"e_1_2_6_81_1","unstructured":"2009 World Health Organization Geneva Switzerland World Health Organization Global Health Risks: Mortality and Burden of Disease Attributable to Selected Major Risks"}],"container-title":["Alcoholism: Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acer.14053","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acer.14053","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acer.14053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T13:22:23Z","timestamp":1694352143000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acer.14053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,9]]},"references-count":80,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1111\/acer.14053"],"URL":"https:\/\/doi.org\/10.1111\/acer.14053","archive":["Portico"],"relation":{},"ISSN":["0145-6008","1530-0277"],"issn-type":[{"value":"0145-6008","type":"print"},{"value":"1530-0277","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,9]]},"assertion":[{"value":"2018-12-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}