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We aimed to determine whether the associations between alcohol use and AUD differ by weight status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 24,869 adult participants of the National Epidemiologic Survey on Alcohol and Related Conditions\u2010III with a body mass index \u226518.5\u00a0kg\/m<jats:sup>2<\/jats:sup> who reported past\u2010year alcohol use were included. The AUD and Associated Disabilities Interview Schedule\u20105 were administered to identify past\u2010year AUD. Logistic regression was used to test the associations between weight status and levels and patterns of alcohol use with AUD; interactions between weight status and alcohol use variables in relation to AUD were examined. Analyses were stratified by gender.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For males and females, the odds of AUD were higher with greater frequency of any alcohol use and heavy drinking, higher average quantity of drinks per drinking day, and past\u2010year high\u2010risk drinking. Among males, at the same average quantity of drinks per drinking day, frequency of heavy drinking, or presence of high\u2010risk drinking, those with class 3 obesity had higher odds of AUD versus lower classes or no obesity (<jats:italic>p<\/jats:italic> for all interactions &lt;0.01). Among females, at the same frequency of any alcohol use, those with healthy weight had the highest odds of AUD, while females with class 3 obesity had the lowest odds of AUD (<jats:italic>p<\/jats:italic> for interaction &lt;0.001); interactions between weight status and other alcohol use variables were not significant (<jats:italic>p<\/jats:italic>\u00a0\u2265\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The associations between some measures of alcohol use and AUD differed by weight status, with inconsistent results between males and females. Alcohol use thresholds typically used in AUD screening may be too high in males with class 3 obesity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.14071","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T01:23:14Z","timestamp":1556673794000},"page":"1498-1509","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Do Associations Between Alcohol Use and Alcohol Use Disorder Vary by Weight Status? Results From the National Epidemiologic Survey on Alcohol and Related Conditions\u2010III"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2772-5736","authenticated-orcid":false,"given":"Gretchen E.","family":"White","sequence":"first","affiliation":[{"name":"Department of Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gale A.","family":"Richardson","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pittsburgh School of Medicine Pittsburgh Pennsylvania"},{"name":"Department of Epidemiology University of Pittsburgh Graduate School of Public Health Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Mair","sequence":"additional","affiliation":[{"name":"Department of Behavioral and Community Health Sciences University of Pittsburgh Graduate School of Public Health Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita P.","family":"Courcoulas","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pittsburgh School of Medicine Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy C.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Pittsburgh Graduate School of Public Health Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867323666161202092908"},{"key":"e_1_2_7_3_1","unstructured":"AgrawalA LittlefieldA VergesA SherKJ(2018)The Alcohol Use Disorder and Associated Disabilities Interview Schedule\u2014Diagnostic and Statistical Manual of Mental Disorders\u2014Fifth Edition Version (AUDADIS\u20135) Alcohol and Drug Use Disorders Scoring Algorithms[Online]. 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