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We obtained a peak phlebotomy BAC and measured breath alcohol concentration (BrAC) with a police\u2010grade device (Intoxilyzer 240) and two randomly ordered series of 3 consumer smartphone\u2010paired devices (6 total devices) with measurements every 20\u00a0min until the BrAC reached &lt;0.02% on the police device. Ten participants tested the first 3 devices, and the other 10 participants tested the other 3 devices. We measured mean paired differences in BrAC with 95% confidence intervals between the police\u2010grade device and consumer devices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The enrolled sample (<jats:italic>N<\/jats:italic>\u00a0=\u00a020) included 11 females; 15 white, 3 Asian, and 2 Black participants; with a mean age of 27 and mean BMI of 24.6. Peak BACs ranged from 0.06\u20130.14%. All 7 devices underestimated BAC by &gt;0.01%, though the BACtrack Mobile Pro and police\u2010grade device were consistently more accurate than the Drinkmate and Evoc. Compared with the police\u2010grade device measurements, the BACtrack Mobile Pro readings were consistently higher, the BACtrack Vio and Alcohoot measurements similar, and the Floome, Drinkmake, and Evoc consistently lower. The BACtrack Mobile Pro and Alcohoot were most sensitive in detecting BAC driving limit thresholds, while the Drinkmate and Evoc devices failed to detect BAC limit thresholds more than 50% of the time relative to the police\u2010grade device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The accuracy of smartphone\u2010paired devices varied widely in this laboratory study of healthy participants. Although some devices are suitable for clinical and research purposes, others underestimated BAC, creating the potential to mislead intoxicated users into thinking that they are fit to drive.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.14597","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T15:00:16Z","timestamp":1620572416000},"page":"1091-1099","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Accuracy of Consumer\u2010marketed smartphone\u2010paired alcohol breath testing devices: A laboratory validation study"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2248-8401","authenticated-orcid":false,"given":"Mucio Kit","family":"Delgado","sequence":"first","affiliation":[{"name":"Behavioral Science &amp; Analytics For Injury Reduction (BeSAFIR) Lab Department of Emergency Medicine &amp; the Center for Health Incentives and Behavioral Economics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"},{"name":"Department of Biostatistics, Epidemiology, and Informatics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"},{"name":"Penn Injury Science Center University of Pennsylvania Philadelphia PA USA"},{"name":"Leonard Davis Institute of Health Economics University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Shofer","sequence":"additional","affiliation":[{"name":"Behavioral Science &amp; Analytics For Injury Reduction (BeSAFIR) Lab Department of Emergency Medicine &amp; the Center for Health Incentives and Behavioral Economics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reagan","family":"Wetherill","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2511-3322","authenticated-orcid":false,"given":"Brenda","family":"Curtis","sequence":"additional","affiliation":[{"name":"Technology and Translational Research Unit National Institute on Drug Abuse National Institutes of Health Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Hemmons","sequence":"additional","affiliation":[{"name":"Behavioral Science &amp; Analytics For Injury Reduction (BeSAFIR) Lab Department of Emergency Medicine &amp; the Center for Health Incentives and Behavioral Economics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Spencer","sequence":"additional","affiliation":[{"name":"Behavioral Science &amp; Analytics For Injury Reduction (BeSAFIR) Lab Department of Emergency Medicine &amp; the Center for Health Incentives and Behavioral Economics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Branas","sequence":"additional","affiliation":[{"name":"Penn Injury Science Center University of Pennsylvania Philadelphia PA USA"},{"name":"Department of Epidemiology Mailman School of Public Health Columbia University New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas J.","family":"Wiebe","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, and Informatics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"},{"name":"Penn Injury Science Center University of Pennsylvania Philadelphia PA USA"},{"name":"Leonard Davis Institute of Health Economics University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1018-0450","authenticated-orcid":false,"given":"Henry R.","family":"Kranzler","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia PA USA"},{"name":"VISN 4 Mental Illness Research, Education, and Clinical Center (MIRECC) Crescenz VA Medical Center Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.12093"},{"key":"e_1_2_7_3_1","article-title":"Amazon Has Ceded Control of Its Site. 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