{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:34:39Z","timestamp":1791819279610,"version":"4.3.4"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01\u2010AA013746"],"award-info":[{"award-number":["R01\u2010AA013746"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R21\u2010AA024901"],"award-info":[{"award-number":["R21\u2010AA024901"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcoholism Clin &amp;amp; Exp Res"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>For decades, laboratory alcohol challenges have been the \u201cgold standard\u201d for measuring individual differences in alcohol's subjective effects. However, these approaches are expensive and labor\u2010intensive, making them impractical for large\u2010scale use. This study examined the reliability and validity of a new high\u2010resolution EMA (HR\u2010EMA) ambulatory approach to assessing alcohol use and subjective responses in drinkers\u2019 natural environments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were 83 young adult heavy social drinkers (58% male; mean\u00a0\u00b1\u00a0SD age\u00a0=\u00a025.4\u00a0\u00b1\u00a02.6\u00a0years) who completed up to two smartphone\u2010based, 3\u2010h HR\u2010EMA assessments of alcohol use and related subjective responses in their typical drinking environments. Reported alcohol consumption during the HR\u2010EMA periods was used to calculate estimated blood alcohol concentration (eBAC). Subjective effects were measured using the Brief Biphasic Alcohol Effects Scale (B\u2010BAES) and Drug Effects Questionnaire (DEQ). All participants also completed identical measures during a separate, 4 to 5\u2010h laboratory session in which they received a 0.8\u00a0g\/kg alcohol challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most natural environment drinking episodes (87%) met or exceeded the threshold for binge drinking (final mean eBAC\u00a0=\u00a00.12\u00a0g\/dl). Associations between reported alcohol use and subjective responses on the B\u2010BAES and DEQ were strongest earlier in the drinking events, with fair reliability of reported subjective effects across two HR\u2010EMA episodes (intraclass correlation [ICC] range = 0.46\u22120.49). There was fair\u2010to\u2010good correspondence between HR\u2010EMA\u2010 and laboratory\u2010derived subjective responses (ICC range = 0.49\u22120.74), even after accounting for differences in alcohol consumption and drinking context. Reported stimulating and rewarding alcohol effects were higher in the ambulatory than laboratory setting, and vice versa for sedating effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study supports the reliability and validity of smartphone\u2010based HR\u2010EMA to measure alcohol use and subjective responses in heavy drinkers\u2019 natural environments. These findings lend support to the use of ambulatory HR\u2010EMA as a measure of alcohol subjective responses in risky drinkers when a laboratory protocol is not practical, feasible, or safe.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.14616","type":"journal-article","created":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T08:08:19Z","timestamp":1618646899000},"page":"1287-1297","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Alcohol subjective responses in heavy drinkers: Measuring acute effects in the natural environment versus the controlled laboratory setting"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3451-1418","authenticated-orcid":false,"given":"Daniel J.","family":"Fridberg","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Neuroscience The University of Chicago Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5529-0960","authenticated-orcid":false,"given":"Dingcai","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences University of Illinois at Chicago Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5943-7109","authenticated-orcid":false,"given":"Andrea C.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neuroscience The University of Chicago Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-019-05262-8"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-017-4727-1"},{"key":"e_1_2_7_5_1","first-page":"14","article-title":"Vital Signs: binge drinking prevalence, frequency, and intensity among adults\u2014United States, 2010","volume":"61","author":"Centers for Disease Control and Prevention","year":"2011","journal-title":"Mortality and Morbidity Weekly Report"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.6.4.284"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2016.08.623"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.14305"},{"key":"e_1_2_7_9_1","volume-title":"Structured Clinical Interview for DSM\u20105\u2014Research Version (SCID\u20105 for DSM\u20105, Research Version; 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