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We focused on an important clinical population\u2013past\u2010year drinkers with unhealthy alcohol use\u2013i.e., those with a positive score on the Alcohol Use Disorders Identification Test\u2013Consumption (AUDIT\u2010C) questionnaire. We also examined the association of AWS with sociodemographic measures, psychiatric disorders, alcohol\u2010related measures, and healthcare utilization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Approximately one\u2010third (<jats:italic>n<\/jats:italic>\u00a0=\u00a012,634) of respondents reported unhealthy alcohol use (AUDIT\u2010C+). Of these, 14.3% met criteria for a DSM\u20105 AWS diagnosis. The mean (SE) number of withdrawal symptoms among individuals with AWS was 2.83 (1.88), with the most common being nausea\/vomiting and insomnia (19.8% and 11.6%, respectively). Among AUDIT\u2010C+ respondents, the odds of AWS were significantly higher among males (adjusted odds ratio [aOR]\u00a0=\u00a01.17 [95% CI, 1.02\u20131.33]), unmarried participants (aOR\u00a0=\u00a01.55 [95% CI, 1.25\u20131.92]), and those at the lowest (vs. highest) income levels (aOR\u00a0=\u00a01.62 [95% CI, 1.37\u20131.92]). Among AUDIT\u2010C+ respondents, AWS was also associated with psychiatric disorders (with aORs that ranged from 2.08 [95% CI, 1.79\u20132.41]) for major depressive disorder to 3.14 (95% CI, 1.79\u20132.41) for borderline personality disorder. AUDIT\u2010C+ respondents with AWS also had higher odds of past\u2010year alcohol use disorder (aOR\u00a0=\u00a011.2 [95% CI, 9.66\u201313.07]), other alcohol\u2010related features (e.g., binge drinking), and healthcare utilization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among individuals with unhealthy alcohol use, AWS is prevalent, highly comorbid, and disabling. Given the risk of AWS among unhealthy drinkers, a comparatively large segment of the general population, clinicians should seek to identify individuals with AWS and intervene with them to prevent serious adverse outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.14781","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T15:10:25Z","timestamp":1647011425000},"page":"422-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Alcohol withdrawal in past\u2010year drinkers with unhealthy alcohol use: Prevalence, characteristics, and correlates in a national epidemiologic survey"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6673-0231","authenticated-orcid":false,"given":"Ofir","family":"Livne","sequence":"first","affiliation":[{"name":"Department of Epidemiology Columbia University Mailman School of Public Health  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4158-7640","authenticated-orcid":false,"given":"Richard","family":"Feinn","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences Frank H. Netter School of Medicine at Quinnipiac University  North Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6771-8138","authenticated-orcid":false,"given":"Justin","family":"Knox","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"New York State Psychiatric Institute HIV Center for Clinical and Behavioral Studies  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5137-9714","authenticated-orcid":false,"given":"Emily E.","family":"Hartwell","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pennsylvania Perelman School of Medicine and Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center  Philadelphia Pennsylvania 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