{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T03:16:44Z","timestamp":1771125404819,"version":"3.50.1"},"reference-count":55,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T00:00:00Z","timestamp":1654473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001322","name":"South African Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcoholism Clin &amp;amp; Exp Res"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Facial imaging tools have rapidly advanced in recent years and show potential for use in fetal alcohol spectrum disorder (FASD) screening and diagnosis. This scoping review describes the current state of evidence regarding the use of facial imaging being as a screening tool for FASD at a community level. This review follows the\u00a0guidelines for the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analysis (PRISMA) extension for scoping reviews and is registered with the Open Science Framework (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/osf.io\/e4xw6\">osf.io\/e4xw6<\/jats:ext-link>). An electronic search of five databases was conducted. The time frame was limited to the period 2006 to 2022. The search included any form of imaging of the head, neck, oral cavity, and dentition. Animal and antenatal studies were excluded, as were those using only brain imaging. The search retrieved 730 unique titles. After title, abstract, and full\u2010text screening, 28 primary studies were included in this review. Most studies were conducted with South African participants. Imaging included 2D photographs, 3D stereophotogrammetry, 3D laser scanning, and radiographs. Various measurements and landmarks were used to discriminate FASD from non\u2010FASD participants, which included anthropometry, face shape analysis, and facial curvatures. Methods of data processing, analysis, and modeling ranged from manual methods to fully automated systems utilizing artificial intelligence. The use of facial imaging to screen for and diagnose patients with FASD is a rapidly advancing field. Most studies in the field remain exploratory, attempting to find accurate, reliable, and consistent landmarks and measures across different populations. For community screening, none of the tools in this review in their current form completely fulfill all the identified properties of an ideal screening tool. More research and development are needed prior to advocating for the use of any tool listed and the ethical implications are yet to be fully explored.<\/jats:p>","DOI":"10.1111\/acer.14875","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T13:07:03Z","timestamp":1653570423000},"page":"1166-1180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Facial imaging to screen for fetal alcohol spectrum disorder: A\u00a0scoping review"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6789-5484","authenticated-orcid":false,"given":"Imaan","family":"Roomaney","sequence":"first","affiliation":[{"name":"Department of Craniofacial Biology, Faculty of Dentistry University of Western Cape  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clement","family":"Nyirenda","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Faculty of Natural Science University of Western Cape  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manogari","family":"Chetty","sequence":"additional","affiliation":[{"name":"Department of Craniofacial Biology, Faculty of Dentistry University of Western Cape  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,6]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"44","article-title":"High facial specificity and positive predictive value are required to diagnose fetal alcohol syndrome when prenatal alcohol exposure is unknown","volume":"7","author":"Astley Hemingway S.","year":"2020","journal-title":"Advances in Pediatric 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