{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T07:21:11Z","timestamp":1760080871530,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["K23 AA028297","R21 AA028576"],"award-info":[{"award-number":["K23 AA028297","R21 AA028576"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcohol: Clinical and Experimental Research"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Metabolic dysfunction\u2010associated steatotic liver disease (MASLD) and alcohol consumption have both increased in recent years, and there is debate as to whether nonheavy alcohol use is safe in MASLD. We analyzed the association between different nonheavy alcohol use patterns and at\u2010risk liver fibrosis among individuals with MASLD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a cross\u2010sectional study of 1072 eligible National Health and Nutrition Examination Survey participants with MASLD who reported nonheavy alcohol consumption. We used vibration\u2010controlled transient elastography to define the primary outcome of at\u2010risk liver fibrosis as &gt;8.2\u2009kPa (stage F2\u2010F4). Multivariable logistic regression models were used to determine the association of different alcohol consumption patterns (average drinks\/day, drinking days\/week, weekly alcohol intake, type of alcoholic beverage) and at\u2010risk hepatic fibrosis, controlling for demographic\/socioeconomic, lifestyle\/dietary, and metabolic risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Exclusive liquor or cocktail drinkers had a 5.02\u2010fold odds of at\u2010risk fibrosis (95% CI: 1.15\u201321.95) compared with non\u2010drinkers when controlling for potential confounders. While consuming an average of 2 drinks\/day, \u22653 drinking days\/week, or 1\u20133 drinks\/week appeared to have a lower association with at\u2010risk fibrosis when controlling for demographic\/socioeconomic risk factors, the association was not present after controlling for lifestyle\/dietary and metabolic risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is an association between exclusive liquor\/cocktail consumption and at\u2010risk liver fibrosis in patients with MASLD who report nonheavy alcohol consumption.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.15220","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T08:28:32Z","timestamp":1699259312000},"page":"88-97","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Exclusive liquor and cocktail consumption is associated with at\u2010risk fibrosis among nonheavy alcohol users with metabolic dysfunction\u2010associated steatotic liver disease"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1581-2354","authenticated-orcid":false,"given":"Peng\u2010sheng","family":"Ting","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Tulane University School of Medicine  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Ting","family":"Lin","sequence":"additional","affiliation":[{"name":"Social, Behavioral, and Population Sciences Tulane University School of Public Health and Tropical Medicine  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6331-7898","authenticated-orcid":false,"given":"Chiung\u2010Kuei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pathology Tulane University School of Medicine  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3307-5549","authenticated-orcid":false,"given":"Hui\u2010Yi","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Public Health Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6266-9891","authenticated-orcid":false,"given":"Tung\u2010Sung","family":"Tseng","sequence":"additional","affiliation":[{"name":"School of Public Health Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po\u2010Hung","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.01.026"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23527"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.32101"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000003"},{"key":"e_1_2_10_6_1","unstructured":"Centers for Disease Control and Prevention (CDC)&National Center for Health Statistics (NCHS). 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