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However, the effects of prenatal alcohol exposure on sleep quality have been understudied, despite reports of sleep disturbance in infants prenatally exposed to alcohol and elevated levels of sleep problems reported by caregivers of children with fetal alcohol spectrum disorders. The current study characterizes sleep in children with prenatal alcohol exposure using both objective (actigraphy) and subjective (questionnaires, sleep diaries) methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants aged 6\u201310\u2009years, with and without prenatal alcohol exposure, were included in the study (alcohol\u2010exposed [AE]: n\u2009=\u200935; control [CON]: n\u2009=\u200939). Objective sleep was measured via 24\u2010h actigraphy for 2\u2009weeks. Parents completed sleep diaries and sleep questionnaires (Children's Sleep Habits Questionnaire, Pediatric Sleep Questionnaire). Multivariate analysis of variance was used to characterize the sleep profile (objective, subjective) and examine group differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no group differences on actigraphy metrics averaged across 2\u2009weeks. However, the AE group showed significantly greater intraindividual variability on most actigraphy measures, particularly total sleep time, percent sleep, wake after sleep onset, and number of wake bouts. Parents reported significantly more sleep problems in the AE group than in the CON group, primarily driven by night wakings, parasomnias (e.g., sleepwalking), snoring, and daytime sleepiness. These effects were more severe in children &gt;8.5\u2009years of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite similar 2\u2010week average sleep outcomes, children with prenatal alcohol exposure showed greater intraindividual sleep variability and parents reported more sleep problems related to sleep behavior and snoring. These difficulties with sleep may be related to other cognitive and behavioral outcomes. Importantly, sleep is a modifiable behavior, and interventions that focus on variability in sleep, particularly in sleep duration, can impact the quality of life in children with prenatal alcohol exposure and their families.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acer.15303","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T03:09:20Z","timestamp":1711336160000},"page":"928-943","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Characteristics of sleep in children with heavy prenatal alcohol exposure"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4015-6267","authenticated-orcid":false,"given":"Sarah M.","family":"Inkelis","sequence":"first","affiliation":[{"name":"Department of Neurology University of California San Francisco  San Francisco California 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