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However, over the years, it has been considered an adaptive process that allows people to avoid retrieval of undesirable memories, preventing them from suffering and discomfort. Evidence shows that the ability to suppress memories is affected by several psychopathological conditions characterized by persistent unwanted thoughts, including anxiety and posttraumatic stress disorders. Nevertheless, memory suppression (MS) mechanisms in addiction\u2014a clinical condition characterized by recurrent drug\u2010related thoughts that contribute to repeated drug use\u2014have received little attention so far. Addiction theories reveal that drugs change behavior by working on memory systems, particularly on declarative memory, which is related to the retrieval and encoding of drug\u2010related memories. In this review, the main behavioral and neurofunctional findings concerning the Think\/No\u2010Think task\u2014an adaptation of the classical Go\/No\u2010Go tasks typically used to evaluate the suppression of motor response\u2014are presented. We then show how the memory system can be involved in the craving or anticipation\/preoccupation stage of the addiction cycle. Subsequently, the study of MS in the context of addictive behaviors is highlighted as a promising approach for gaining knowledge about the mechanisms contributing to the continuation of addiction. Finally, we discuss how interventions aiming to strengthen this ability could impact the anticipation\/preoccupation stage by (i) reducing the accessibility of drug\u2010related memories, (ii) decreasing craving and attention toward drug\u2010related stimuli, and (iii) improving overall inhibition abilities. In conclusion, this review aims to illustrate how the study of MS may be a valuable approach to enhance our understanding of substance use disorders by unveiling the underlying cognitive and neural mechanisms involved, which could have important implications for addiction treatment.<\/jats:p>","DOI":"10.1111\/acer.15381","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T03:21:22Z","timestamp":1717730482000},"page":"1421-1442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Tackling addictive behaviors through memory suppression: A scoping review and perspective"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3546-2120","authenticated-orcid":false,"given":"Nat\u00e1lia Alexandra","family":"de Almeida\u2010Antunes","sequence":"first","affiliation":[{"name":"Psychological Neuroscience Laboratory (PNL), Psychology Research Center (CIPsi), School of Psychology University of Minho  Braga Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7347-1282","authenticated-orcid":false,"given":"Adriana Concei\u00e7\u00e3o Soares","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Psychological Neuroscience Laboratory (PNL), Psychology Research Center (CIPsi), School of Psychology University of Minho  Braga Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6621-690X","authenticated-orcid":false,"given":"Manuel Alberto Barreiro","family":"Crego","sequence":"additional","affiliation":[{"name":"Psychological Neuroscience Laboratory (PNL), Psychology Research Center (CIPsi), School of Psychology University of Minho  Braga Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1788-1556","authenticated-orcid":false,"given":"Eduardo Guillermo","family":"L\u00f3pez\u2010Caneda","sequence":"additional","affiliation":[{"name":"Psychological Neuroscience Laboratory (PNL), Psychology Research Center (CIPsi), School of Psychology University of Minho  Braga Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","unstructured":"Almeida\u2010Antunes N. 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