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Although antisocial conduct may increase exposure to known social and environmental risk factors for developing alcohol use disorder (AUD), alcohol use may also impair social functioning and self\u2010regulation that subsequently increases ASB risk. Using a sibling comparison design in a high\u2010risk sample, this study tested bidirectional associations between symptom counts of ASB and AUD from adolescence through adulthood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Participants were a sample of 783 probands with adolescent\u2010onset ASB and AUD symptoms at baseline and 556 of their siblings assessed during adolescence (18\u2009years and younger), emerging adulthood (19\u201326\u2009years), and later adulthood (27\u2009years and older). We applied multilevel cross\u2010lagged panel models to assess lagged associations between ASB and AUD symptoms across three waves. Clustering was specified at the family level, with outcomes centered within families.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Greater within\u2010family ASB in adolescence predicted moderate increases in AUD in emerging adulthood (<jats:italic>\u00df<\/jats:italic>\u2009=\u20090.25, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001); whereas adolescent AUD did not predict subsequent ASB. Within\u2010family associations between AUD and ASB were not found in the emerging\u2010to\u2010later adult periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Accounting for family\u2010level confounding, ASB symptoms in adolescence may be a precursor to AUD in emerging adulthood; whereas AUD and ASB symptoms may follow independent trajectories through adulthood. 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