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This study examined whether alcohol consumption reported on the three\u2010item Alcohol Use Disorder Identification Test, Consumption (AUDIT\u2010C) during routine care was associated with all\u2010cause mortality, and secondarily, whether age and sex modified associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study used electronic health record data from a large integrated health system and death data from the Washington Department of Health. Adult (\u226518\u2009years) primary care patients were included if they completed an AUDIT\u2010C screen (March 1, 2015\u2013December 31, 2021). AUDIT\u2010C scores were categorized: no alcohol use (0), low\u2010risk alcohol use (1\u20132 female\/1\u20133 male), moderate\u2010risk alcohol use (3\u20136 female\/4\u20136 male), high\u2010risk alcohol use (7\u20138), or very high\u2010risk alcohol use (9\u201312). Time\u2010to\u2010event (death or censoring) was measured for up to 8\u2009years (2015\u20132023). Cox proportional hazards models, adjusted for demographic and clinical covariates, estimated adjusted all\u2010cause mortality across AUDIT\u2010C score categories, with low\u2010risk alcohol use as the reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 531,851 primary care patients, a majority were aged 30\u201359 (52%), female (58%), non\u2010Hispanic (94%), and White (70%). A total of 21,548 patients died (4.8%) during follow\u2010up (median 1752\u2009days). Compared to patients reporting low\u2010risk alcohol use, those reporting no use or very high\u2010risk use had higher mortality (hazard ratio [HR]\u2009=\u20091.40 [95% CI: 1.36\u20131.44] and HR\u2009=\u20091.58 [1.35\u20131.84], respectively); those with moderate\u2010risk use had lower mortality (HR\u2009=\u20090.86 [0.83\u20130.90]). Associations varied by age (stronger among young adults) but not sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Alcohol use reported on brief screens during routine primary care had an approximately convex association (J\u2010 or U\u2010shaped depending on sub\u2010population) with all\u2010cause mortality as observed in prior epidemiological studies. Findings support the value of routine alcohol screening as a tool for identifying patients at risk for major adverse health outcomes like death.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.70192","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T07:50:15Z","timestamp":1764748215000},"page":"2875-2886","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Alcohol consumption reported on routine healthcare screenings is associated with all\u2010cause mortality in primary care patients: A retrospective cohort study"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4551-7981","authenticated-orcid":false,"given":"Theresa E.","family":"Matson","sequence":"first","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute  Seattle Washington USA"},{"name":"Department of Health Systems and Population Health University 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