{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:52:09Z","timestamp":1789555929677,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcohol, Clinical and Experimental Research"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The prehospital assessment and subsequent therapeutic interventions are crucial for the optimal management of severely injured patients. Many trauma patients are alcohol\u2010intoxicated. Therefore, this study investigated the prehospital assessment of the injury pattern and management of alcohol\u2010intoxicated patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a retrospective matched\u2010pair analysis of TraumaRegister DGU\u00ae data patients from 2015 to 2018 with a blood alcohol level (BAL+)\u2009&gt;\u20091.0\u2030 and without a blood alcohol level (BAL\u2212: 0.0\u2030) were investigated, matched by age, gender, injured region, and mechanism. We evaluated injury assessment, prehospital therapy, and transport modalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 6468 patients (3234 BAL\u2212, 3234 BAL+) were included. Head injuries were common (56.9%), but BAL+ patients were significantly less often correctly assessed with regard to head (BAL\u2212: 77.8% vs. BAL+: 74.2%) and facial (BAL\u2212: 75.4% vs. BAL+: 70.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) injuries. Head and facial injuries were significantly more often improperly overdiagnosed in alcohol\u2010intoxicated patients (head: BAL\u2212: 13.9% vs. BAL+: 21.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05; face: BAL\u2212: 19.8% vs. BAL+: 24.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and the diagnosis of actual head injuries was underdiagnosed significantly more often in patients with BAL+. Alcohol\u2010intoxicated patients were sedated (BAL\u2212: 64.9% vs. BAL+: 55.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and intubated (BAL\u2212: 39.0% vs. BAL+: 28.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) significantly less often and received significantly less fluid therapy (BAL\u2212: 92.6% vs. BAL+: 90.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), catecholamines (BAL\u2212: 12.7% vs. BAL+: 8.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), or tranexamic acid (BAL\u2212: 10.3% vs. BAL+: 6.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Admission of alcohol\u2010intoxicated patients to hospital was significantly more frequent at weekends and at night, and more frequent in regional and local trauma centers than in supraregional trauma centers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There were significant differences in the prehospital assessment of head injuries between alcohol\u2010intoxicated and nonalcohol\u2010intoxicated patients. Alcohol\u2010intoxicated patients were significantly less often correctly assessed, and alcohol\u2010intoxicated patients received fewer prehospital therapeutic interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.70209","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T15:01:11Z","timestamp":1769180471000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The influence of alcohol on prehospital diagnostics and therapy of injured patients"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7544-9770","authenticated-orcid":false,"given":"Ramona","family":"Sturm","sequence":"first","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics University Hospital, Goethe\u2010University Frankfurt  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason\u2010Alexander","family":"H\u00f6rauf","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics University Hospital, Goethe\u2010University Frankfurt  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Lefering","sequence":"additional","affiliation":[{"name":"Institute for Research in Operative Medicine (IFOM) University Witten\/Herdecke  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borna","family":"Relja","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Trauma, Hand\u2010, Plastic\u2010, and Reconstructive Surgery, Translational and Experimental Trauma Research University Ulm  Ulm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Marzi","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics University Hospital, Goethe\u2010University Frankfurt  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Trauma Surgery and Orthopedics University Hospital, Goethe\u2010University Frankfurt  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The TraumaRegister DGU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(80)90431-6"},{"key":"e_1_2_7_3_1","unstructured":"Bernhard M. Bein B. B\u00f6ttiger B. Bohn A. Fischer M. Gr\u00e4sner J.et\u00a0al. (2015)Handlungsempfehlung zur pr\u00e4hospitalen Notfallnarkose beim Erwachsenen. S1 Leitlinie AWMF\u2010Register Nr. 001\/030. AWMF Online."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-021-00916-z"},{"key":"e_1_2_7_5_1","unstructured":"Deutsche Gesellschaft f\u00fcr Unfallchirurgie. (2019)Wei\u00dfbuch Schwerverletztenversorgung3. erweiterte Auflage."},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-009-0266-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-2897-8-7"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-021-01643-x"},{"key":"e_1_2_7_9_1","first-page":"39","article-title":"Urgency of neurosurgical interventions for severe traumatic brain injury","volume":"116","author":"K\u00fchne C.A.","year":"2013","journal-title":"Unfallchirurg"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-014-0476-2"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000001782"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2022.08.013"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00101-010-1846-z"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31818234bf"},{"key":"e_1_2_7_15_1","first-page":"3","volume-title":"Level 3 guideline on the treatment of patients with severe\/multiple injuries","author":"Polytrauma Guideline Update Group","year":"2018"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2016.01.016"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-74753-y"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-7241-20-64"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000250413.41265.d3"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-024-02732-3"},{"key":"e_1_2_7_21_1","unstructured":"TraumaRegister DGU\u00ae. (2024)Jahresbericht."},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-45400"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-019-01231-0"},{"key":"e_1_2_7_24_1","unstructured":"World Health Organization. (2024)Injuries and violences. Available from:https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/injuries\u2010and\u2010violence[Accessed 19th June 2024]."}],"container-title":["Alcohol, Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acer.70209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acer.70209","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acer.70209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:23:04Z","timestamp":1772986984000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acer.70209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/acer.70209"],"URL":"https:\/\/doi.org\/10.1111\/acer.70209","archive":["Portico"],"relation":{},"ISSN":["2993-7175","2993-7175"],"issn-type":[{"value":"2993-7175","type":"print"},{"value":"2993-7175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-02-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70209"}}