{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T07:06:55Z","timestamp":1779088015288,"version":"3.51.4"},"reference-count":54,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T00:00:00Z","timestamp":1775952000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01AA029386"],"award-info":[{"award-number":["R01AA029386"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcohol, Clinical and Experimental Research"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Environmental cues can become conditioned stimuli when associated with alcohol consumption, facilitating alcohol\u2010seeking behavior and increasing relapse risk. Extinguishing alcohol\u2010seeking behavior may reduce cue\u2010induced responses; however, conditioned responding often occurs when the cue is presented in a different context than the one where the behavior was extinguished. Although prior research suggests that males generally show stronger context\u2010dependent return of conditioned appetitive and fear responses, it is not known whether this sex difference extends to conditioned responses to alcohol\u2010associated cues.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>After a 5\u2010week alcohol induction period, adult male and female Long\u2013Evans rats underwent Pavlovian conditioning in Context A, where a 15% unsweetened alcohol solution was paired with a light cue. Extinction sessions were conducted in a distinct Context B in the absence of alcohol, followed by a test session in Context B (LTM) and then in Context A.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both sexes successfully extinguished alcohol\u2010seeking behavior in Context B but exhibited robust alcohol\u2010seeking behavior when reintroduced to the alcohol\u2010associated context, Context A. No significant sex differences were observed in the magnitude of reemerged conditioned responding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that changes of context induce alcohol\u2010seeking behavior to return similarly in male and female rats, indicating that sex\u2010independent mechanisms may underlie contextual relapse processes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.70296","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T05:22:58Z","timestamp":1776057778000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Context\u2010Dependent Extinction and Return of Pavlovian Alcohol\u2010Seeking Behavior in Male and Female Rats"],"prefix":"10.1111","volume":"50","author":[{"given":"Taylor 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