{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T12:18:20Z","timestamp":1788178700932,"version":"build-2803163510"},"reference-count":55,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01AA024628"],"award-info":[{"award-number":["R01AA024628"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01AA024628\u201005S1"],"award-info":[{"award-number":["R01AA024628\u201005S1"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcohol, Clinical and Experimental Research"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Despite strong links between emotion regulation (ER) difficulties and problem drinking, few studies have directly addressed whether interventions that target ER positively impact drinking outcomes. In a prior Stage 1a\/1b behavioral therapies development study, we developed an Emotion Regulation Treatment (ERT) for alcohol use disorder (AUD) that included strategies addressing prolonged direct experiencing of emotion, mindfulness, and coping and distress tolerance. Results demonstrated the feasibility and initial efficacy of ERT as a supplement to cognitive behavioral therapy (CBT) for AUD. Based on this initial success, the current study reports on a fully powered stage II randomized clinical efficacy trial to compare CBT plus ERT (CBT\u2009+\u2009ERT) to CBT plus an active health and lifestyles (HLS) control (CBT\u2009+\u2009HLS) and explore potential mechanisms of action.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Adults (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009194) with moderate\u2010to\u2010severe AUD were enrolled in 12\u2009week outpatient treatment and randomized to either the CBT\u2009+\u2009ERT or CBT\u2009+\u2009HLS treatment condition. Analyses evaluated (1) the impact of treatment condition on percent days abstinent (PDA) and percent heavy drinking days (PHDD) at end of treatment (EOT) and 3, 6, and 12\u2009months posttreatment, and (2) whether change trajectories of negative affect, craving, mindfulness, cognitive reappraisal, or adaptive alcohol coping, assessed daily or weekly during treatment, partially accounted for associations between treatment condition and EOT alcohol outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The CBT\u2009+\u2009ERT group had greater PDA at all posttreatment follow\u2010ups relative to the CBT\u2009+\u2009HLS group. There were no group differences in PHDD. Levels of PDA and PHDD did not change across posttreatment follow\u2010ups for either group. The CBT\u2009+\u2009ERT group exhibited greater adaptive alcohol coping across the first week of treatment, which in turn was associated with higher PDA and lower PHDD at EOT. No other mediation effects were detected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CBT\u2009+\u2009ERT was associated with greater PDA at EOT relative to CBT\u2009+\u2009HLS, an association that was partially explained by greater adaptive coping early in treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.70350","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:02:22Z","timestamp":1785765742000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Emotion Regulation Treatment for Alcohol Use Disorder: Results of a Stage\n                    <scp>II<\/scp>\n                    Randomized Clinical Efficacy Trial"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4737-4133","authenticated-orcid":false,"given":"Kyler S.","family":"Knapp","sequence":"first","affiliation":[{"name":"Department of Community Health and Health Behavior, School of Public Health and Health Professions University at Buffalo  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braden K.","family":"Linn","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine The Pennsylvania State University College of Medicine  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junru","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Social Work University at Buffalo  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory E.","family":"Wilding","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health and Health Professions University at Buffalo  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott F.","family":"Coffey","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Human Behavior University of Mississippi Medical Center  Jackson Mississippi USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzy B.","family":"Gulliver","sequence":"additional","affiliation":[{"name":"Baylor Scott &amp; White Research Institute Warriors Research Institute  Waco Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara M.","family":"Bradizza","sequence":"additional","affiliation":[{"name":"School of Social Work University at Buffalo  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Stasiewicz","sequence":"additional","affiliation":[{"name":"School of Social Work University at Buffalo  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CPR.2009.11.004"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/0893\u2010164x.9.3.176"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2010.535582"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073191107313003"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033\u2010295X.111.1.33"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1037\/pha0000770"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0023421"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2011.09.009"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2017.12.033"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40429\u2010024\u201000553\u20103"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1037\/0893\u2010164X.11.1.26"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.ADDBEH.2019.106035"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10899\u2010024\u201010366\u20108"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1037\/tra0000374"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1037\/\/0022\u20103514.69.5.990"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021\u2010843X.101.1.139"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2013.877920"},{"key":"e_1_2_13_19_1","first-page":"315","volume-title":"Structural Equation Modeling: A Second Course","author":"Enders C. K.","year":"2006"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:JOBA.0000007455.08539.94"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022\u20103514.85.2.348"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1176\/APPI.AJP.21090963"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1037\/emo0001496"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/10705519909540118"},{"key":"e_1_2_13_25_1","unstructured":"Kadden R. C.Kathleen D.Donovan et\u00a0al.1995.\u201cCognitive\u2010Behavioral Coping Skills Therapy Manual: A Clinical Research Guide for Therapists Treating Individuals With Alcohol Abuse and Dependence.\u201dNIH Publication No. 94\u20103724 Project MATCH Monograph Series 3. National Institute on Alcohol Abuse and Alcoholism."},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000450"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2024.104474"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2024.107987"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/SWR\/SVAE012"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.DRUGALCDEP.2015.08.004"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/JCLP.23279"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000914"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.DRUGALCDEP.2022.109695"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2020.106374"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.01.029"},{"key":"e_1_2_13_36_1","volume-title":"Mplus User's Guide","author":"Muth\u00e9n L. K.","year":"2017"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agad018"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/EAT.22669"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1037\/adb0000509"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/CLIPSY.8.2.133"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360\u20100443.2012.04013.x"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1037\/1082\u2010989X.7.2.147"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976\u2010500X.72352"},{"key":"e_1_2_13_44_1","volume-title":"Alcohol Timeline Followback Users' Manual","author":"Sobell L. C.","year":"1995"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2013.05.012"},{"key":"e_1_2_13_46_1","first-page":"64","article-title":"Affect Regulation Training for Alcohol Use Disorders","volume":"15","author":"Stasiewicz P. R.","year":"2014","journal-title":"Counselor: The Magazine for Addiction and Behavioral Health Professionals"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005\u20107894(05)80210\u20102"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.16001"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1037\/abn0000875"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.54.6.1063"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1978.10480054"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2021.109131"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2019.107569"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/ACER.12797"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/ACER.12800"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1037\/adb0000931"}],"container-title":["Alcohol, Clinical and Experimental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acer.70350","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acer.70350","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acer.70350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:50:31Z","timestamp":1788177031000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acer.70350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":55,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/acer.70350"],"URL":"https:\/\/doi.org\/10.1111\/acer.70350","archive":["Portico"],"relation":{},"ISSN":["2993-7175","2993-7175"],"issn-type":[{"value":"2993-7175","type":"print"},{"value":"2993-7175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2025-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70350"}}