{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T12:18:15Z","timestamp":1788178695557,"version":"build-2803163510"},"reference-count":55,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01AA027477"],"award-info":[{"award-number":["R01AA027477"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alcohol, Clinical and Experimental Research"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Brief Interventions (BIs) in primary care are an effective, evidence\u2010based tool for reducing the cost and harm associated with unhealthy alcohol use. However, little is known about the impact of alcohol BIs on the utilization of acute healthcare services over time. This study aims to examine the association between receiving a BI in the outpatient setting and Emergency Department (ED) and inpatient utilization over 2\u2009years among adults screening positive for unhealthy alcohol use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This population\u2010based, retrospective observational study utilized electronic health record (EHR) data collected between January 1, 2013 and June 30, 2019 of 254,190 adult primary care patients who screened positive for unhealthy alcohol use. Patients were grouped by whether or not they received a BI for unhealthy alcohol use from their primary physician at the index date. ED and inpatient utilization was assessed for each 6\u2010month interval following the index screening up to 24\u2009months. Separate generalized estimating equation (GEE) logistic models with inverse probability treatment weighting (IPTW) were fit to examine the associations between BI receipt and ED and inpatient utilization over the 2\u2010year follow\u2010up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>IPTW GEE models indicated that receiving BI was associated with significantly lower odds of ED (aOR [95% CI] =\u20090.96 [0.94\u20130.98]) and inpatient utilization (aOR [95% CI] =\u20090.96 [0.93\u20131.00]) over the 2\u2010year follow\u2010up period. However, the association between BI and ED utilization attenuated over time, and receiving a BI was only significantly associated with lower inpatient utilization in the first 6 months following index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The observed reductions in ED and inpatient utilization contribute novel insight into the duration of BI's harm\u2010reduction effects. Ultimately, our findings support widespread implementation of BI programs in primary care settings as a means of reducing acute healthcare utilization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acer.70395","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T10:49:46Z","timestamp":1785926986000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Alcohol Brief Intervention and Emergency Department and Inpatient Utilization Over 2\u2009Years"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7600-5866","authenticated-orcid":false,"given":"Andrew M.","family":"Ballester","sequence":"first","affiliation":[{"name":"Kaiser Permanente Bernard J. 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