{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:23:24Z","timestamp":1760984604226},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2013,2,21]],"date-time":"2013-02-21T00:00:00Z","timestamp":1361404800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Acta Neuropsychiatr."],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec id=\"S1601521512000250_abs1\" sec-type=\"general\"><jats:title>Introduction<\/jats:title><jats:p>Tardive Tourette\u2010like syndrome is recognised by the observation of several motor and vocal tics often in individuals receiving psychotropic medications and can happen within 1\u20133 months of treatment.<\/jats:p><\/jats:sec><jats:sec id=\"S1601521512000250_abs2\" sec-type=\"general\"><jats:title>Clinical case<\/jats:title><jats:p>We report a case which is unique in its onset of Tardive Tourette\u2010like syndrome comprising of vocal, motor tics and coprolalia after more than three decades of treatment with combination depot and oral neuroleptics.<\/jats:p><\/jats:sec><jats:sec id=\"S1601521512000250_abs3\" sec-type=\"general\"><jats:title>Discussion<\/jats:title><jats:p>Use of the Naranjo Adverse Drug Reaction Probability Scale indicates a probable relationship between the onset of Tardive Tourettism and the antipsychotic therapy in this patient. This was in contrast to earlier reports which noted earlier onset and partial reversal with termination or change of medications. Clinicians need to pay heed to the emergence of late\u2010onset Tourettism in order to better manage its manifestation and prevent its worsening in the context of holistic care for patients with neuropsychiatric conditions including schizophrenia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acn.12009","type":"journal-article","created":{"date-parts":[[2012,8,30]],"date-time":"2012-08-30T18:12:13Z","timestamp":1346350333000},"page":"122-124","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["<i>De novo<\/i>Tardive Tourette\u2010like syndrome after prolonged combination depot and oral neuroleptic therapy"],"prefix":"10.1017","volume":"25","author":[{"given":"Jegan","family":"Yogaratnam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changqing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daw San San","family":"Thinn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee Kim","family":"Yoong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chai Ling","family":"Khoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang","family":"Sim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,2,21]]},"reference":[{"key":"S1601521512000250_ref20","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-200405000-00001"},{"key":"S1601521512000250_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(02)00260-9"},{"key":"S1601521512000250_ref17","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1176\/ajp.137.10.1267","article-title":"Tardive tourette syndrome in an autistic patient after long\u2010term neuroleptic administration","volume":"137","author":"Stahl","year":"1980","journal-title":"Am J Psychiatry"},{"key":"S1601521512000250_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100036052"},{"key":"S1601521512000250_ref13","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"S1601521512000250_ref11","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.23.4.jnpe35"},{"key":"S1601521512000250_ref10","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e3181c06dad"},{"key":"S1601521512000250_ref8","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.28.10.1064"},{"key":"S1601521512000250_ref6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.6.1191"},{"key":"S1601521512000250_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.63.738.311-a"},{"key":"S1601521512000250_ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-198901000-00017"},{"key":"S1601521512000250_ref2","first-page":"1379","article-title":"Gilles de la tourette's symptoms induced by L\u2010dopa","volume":"48","author":"Klempel","year":"1974","journal-title":"S Afr Med J"},{"key":"S1601521512000250_ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1974.tb02715.x"},{"key":"S1601521512000250_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2003.12.006"},{"key":"S1601521512000250_ref12","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.164.6.839"},{"key":"S1601521512000250_ref16","first-page":"357","article-title":"Tardive dyskinesia with Tourette\u2010like syndrome","volume":"42","author":"Seeman","year":"1981","journal-title":"J Clin Psychiatry"},{"key":"S1601521512000250_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(95)00218-6"},{"key":"S1601521512000250_ref4","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.1.159"},{"key":"S1601521512000250_ref15","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-952040"},{"key":"S1601521512000250_ref7","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1542\/peds.73.6.841","article-title":"Tics and vocalizations in children treated with carbamazepine","volume":"73","author":"Neglia","year":"1984","journal-title":"Pediatrics"}],"container-title":["Acta Neuropsychiatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1601521512000250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T23:16:02Z","timestamp":1643325362000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1601521512000250\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,21]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S1601521512000250"],"URL":"https:\/\/doi.org\/10.1111\/acn.12009","relation":{},"ISSN":["0924-2708","1601-5215"],"issn-type":[{"value":"0924-2708","type":"print"},{"value":"1601-5215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,21]]},"assertion":[{"value":"Copyright \u00a9 Scandinavian College of Neuropsychopharmacology 2013","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}