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There, catatonia has lain in the psychiatric classification for more than a century.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We review the history of catatonia and its present status. In the 1970s, the tie was questioned when catatonia was recognized among those with mood disorders. The recognition of catatonia within the neuroleptic malignant syndrome offered effective treatments of high doses of benzodiazepines and electroconvulsive therapy (<jats:styled-content style=\"fixed-case\">ECT<\/jats:styled-content>), again questioning the tie. A verifying test for catatonia (the lorazepam sedation test) was developed. Soon the syndromes of delirious mania, toxic serotonin syndrome, and the repetitive behaviors in adolescents with autism were recognized as treatable variations of catatonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ongoing studies now recognize catatonia among patients labeled as suffering from the <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>illes de la <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ourette's <jats:styled-content style=\"fixed-case\">s<\/jats:styled-content>yndrome, anti\u2010<jats:styled-content style=\"fixed-case\">NMDAR<\/jats:styled-content> encephalitis, obsessive\u2013compulsive disease, and various mutisms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Applying the treatments for catatonia to patients with these syndromes offers opportunities for clinical relief. Catatonia is a recognizable and effectively treatable neuropsychiatric syndrome. It has many faces. 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