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Effects of early\u2010life stress on treatment outcome are considered, and development of treatments designed to address the neurobiological abnormalities is discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early adversity is associated with abnormalities of several neurobiological systems that are implicated in the development of psychopathology and other medical conditions. Early\u2010life stress negatively impacts treatment outcome, and individuals may require treatments that are specific to this condition.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12143","type":"journal-article","created":{"date-parts":[[2013,5,11]],"date-time":"2013-05-11T01:49:02Z","timestamp":1368236942000},"page":"434-447","source":"Crossref","is-referenced-by-count":117,"title":["The neurobiological correlates of childhood adversity and implications for treatment"],"prefix":"10.1111","volume":"128","author":[{"given":"A. 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