{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T07:04:33Z","timestamp":1792825473607,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,6,6]],"date-time":"2013-06-06T00:00:00Z","timestamp":1370476800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The analysis of time trends in dispensed prescriptions of psychotropic medications for children and adolescents in Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The entire data set of the Danish prescription register covering stimulants, antidepressants, antipsychotics, and anxiolytics used in children and adolescents over a 15\u2010year time span from 1996 to 2010 was analyzed. Both non\u2010adjusted age\u2010standardized prevalence rates and adjusted age\u2010standardized prevalence rates considering the increase in patient numbers over time were calculated, and time trends were assessed based on 105\u00a0908 patient\u2010years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For stimulants, antidepressants, and antipsychotics, the non\u2010adjusted prevalence rates increased significantly. These trends were strongest for the stimulants. However, all adjusted prevalence rates were much lower with the anxiolytics even declining significantly. The prevalence rates of stimulants and antipsychotics were significantly higher among males than females, whereas females received significantly more antidepressants. The increase in prescription rates for both antidepressants and antipsychotics was mainly due to increased use among the 14\u2010 to 17\u2010year\u2010olds. Stratification by diagnoses revealed significantly increasing prevalence rates of dispensed antidepressants and antipsychotics in six major diagnostic indications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although increasing, the unadjusted Danish prevalence rates of dispensed prescriptions of psychotropics for children and adolescents are still lower than in many other Western countries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12155","type":"journal-article","created":{"date-parts":[[2013,6,6]],"date-time":"2013-06-06T08:00:52Z","timestamp":1370505652000},"page":"221-231","source":"Crossref","is-referenced-by-count":73,"title":["Nationwide time trends in dispensed prescriptions of psychotropic medication for children and adolescents in Denmark"],"prefix":"10.1111","volume":"129","author":[{"given":"H.\u2010C.","family":"Steinhausen","sequence":"first","affiliation":[{"name":"Research Unit for Child and Adolescent Psychiatry Aalborg Psychiatric Hospital Aalborg University Hospital Aalborg Denmark"},{"name":"Clinical Psychology and Epidemiology Institute of Psychology University of Basel Basel Switzerland"},{"name":"Department of Child and Adolescent Psychiatry University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Bisgaard","sequence":"additional","affiliation":[{"name":"Research Unit for Child and Adolescent Psychiatry Aalborg Psychiatric Hospital Aalborg University Hospital Aalborg 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