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In this article, we attempt to review the pathophysiology and the clinical approach of lithium tremor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We searched the <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ubmed and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ochrane <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ibrary for relevant articles up to the year 2012. Sixty\u2010four articles including 10 review papers, 3 clinical trials, and 12 case reports were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Lithium tremor is classified as a postural tremor and subcategorized as an exaggerated physiologic tremor. Differential diagnosis includes metabolic abnormalities, benign essential tremor, <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>arkinson's disease, and lithium toxicity. Various methods of evaluating lithium tremor and treatment options are discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When lithium tremor has developed, thorough history taking, physical examination, and blood examination including serum lithium level are needed. Pharmacotherapy is indicated only in patients with disabling tremor.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12171","type":"journal-article","created":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T11:54:44Z","timestamp":1372852484000},"page":"17-23","source":"Crossref","is-referenced-by-count":58,"title":["Lithium tremor revisited: pathophysiology and treatment"],"prefix":"10.1111","volume":"129","author":[{"given":"J. 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