{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:31:35Z","timestamp":1791304295131,"version":"4.3.1"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,11,21]],"date-time":"2015-11-21T00:00:00Z","timestamp":1448064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Sleep problems in bipolar disorder (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>) are common, but reported rates vary from 10% to 80%, depending on definitions, methodologies and management of potential confounding factors. This multicenter study seeks to address these issues and also compares <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> cases with Hypersomnia as well as the more commonly investigated Insomnia and No Sleep Problem groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A cross\u2010sectional comparison of sleep profiles in 563 <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> I and <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> individuals who participated in a structured assessment of demographic, clinical, illness history and treatment variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over 40% cases met criteria for Insomnia and 29% for Hypersomnia. In univariate analysis, Insomnia was associated with <jats:styled-content style=\"fixed-case\">BD II<\/jats:styled-content> depression whilst Hypersomnia was associated with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> I depression or euthymia. After controlling for confounders and covariates, it was demonstrated that Hypersomnia cases were significantly more likely to be younger, have <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> I and be prescribed antidepressants whilst Insomnia cases had longer illness durations and were more likely to be prescribed benzodiazepines and hypnotics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Whilst Insomnia symptoms are common in <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>, Hypersomnia is a significant, frequently underexplored problem. Detailed analyses of large representative clinical samples are critical to extending our knowledge of differences between subgroups defined by sleep profile.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12523","type":"journal-article","created":{"date-parts":[[2015,11,22]],"date-time":"2015-11-22T02:49:04Z","timestamp":1448160544000},"page":"368-377","source":"Crossref","is-referenced-by-count":80,"title":["Sleep problems in bipolar disorders: more than just insomnia"],"prefix":"10.1111","volume":"133","author":[{"given":"M. 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