{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T02:50:29Z","timestamp":1788058229677,"version":"build-2784847793"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,16]],"date-time":"2016-12-16T00:00:00Z","timestamp":1481846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002738","name":"Assistance Publique - H\u00f4pitaux de Paris","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002915","name":"Fondation pour la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Repetitive transcranial magnetic stimulation (<jats:styled-content style=\"fixed-case\">rTMS<\/jats:styled-content>) over the left temporo\u2010parietal region has been proposed as a treatment for resistant auditory verbal hallucinations (<jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content>), but which patients are more likely to benefit from <jats:styled-content style=\"fixed-case\">rTMS<\/jats:styled-content> is still unclear. This study sought to assess the effects of <jats:styled-content style=\"fixed-case\">rTMS<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content>, with a focus on hallucination phenomenology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010seven patients with schizophrenia and medication\u2010resistant <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> participated to a randomized, double\u2010blind, placebo\u2010controlled, add\u2010on <jats:styled-content style=\"fixed-case\">rTMS<\/jats:styled-content> study. The stimulation targeted a language\u2010perception area individually determined using functional magnetic resonance imaging and a language recognition task. <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> were assessed using the hallucination subscale of the Scale for the Assessment of Positive Symptoms (<jats:styled-content style=\"fixed-case\">SAPS<\/jats:styled-content>). The spatial location of <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> was assessed using the Psychotic Symptom Rating Scales.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant improvement in <jats:styled-content style=\"fixed-case\">SAPS<\/jats:styled-content> hallucination subscale score was observed in both actively treated and placebo\u2010treated groups with no difference between both modalities. Patients with external <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> were significantly more improved than patients with internal <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content>, with both modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A marked placebo effect of <jats:styled-content style=\"fixed-case\">rTMS<\/jats:styled-content> was observed in patients with resistant <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content>. Patients with prominent external <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> may be more likely to benefit from both active and placebo interventions. Cortical effects related to non\u2010magnetic stimulation of the auditory cortex are suggested.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12680","type":"journal-article","created":{"date-parts":[[2016,12,17]],"date-time":"2016-12-17T17:07:23Z","timestamp":1481994443000},"page":"228-238","source":"Crossref","is-referenced-by-count":48,"title":["Active and placebo transcranial magnetic stimulation effects on external and internal auditory hallucinations of schizophrenia"],"prefix":"10.1111","volume":"135","author":[{"given":"M.\u2010L.","family":"Paill\u00e8re\u2010Martinot","sequence":"first","affiliation":[{"name":"AP\u2010HP, Department of Adolescent Psychopathology and Medicine Maison de Solenn Cochin Hospital Paris France"},{"name":"INSERM, U 1000, Research unit \u2018Imaging &amp; Psychiatry\u2019 Service Hospitalier Fr\u00e9d\u00e9ric Joliot Orsay France"},{"name":"Universit\u00e9 Paris Descartes Paris France"},{"name":"University Paris\u2010Sud, and University Paris\u2010Saclay 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