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Poisson regression models were used to identify individual and treatment factors associated with new <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content> events. Two multivariate models were built, stratified for the presence or absence of prior <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 302 <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content> were recorded prospectively; the peak incidence was 0\u201312 weeks after commencing treatment. In cases with a prior history of <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content>, risk of <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content> repetition was associated with younger age of first manic episode (<jats:italic>P<\/jats:italic> = 0.03), rapid cycling (<jats:italic>P<\/jats:italic> &lt; 0.001), history of alcohol and\/or substance use disorder (<jats:italic>P<\/jats:italic> &lt; 0.001), number of psychotropic drugs prescribed (<jats:italic>P<\/jats:italic> &lt; 0.001) and initiation of an anticonvulsant at study entry (<jats:italic>P<\/jats:italic> &lt; 0.001). In cases with no previous <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content>, the first <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content> event was associated with rapid cycling (<jats:italic>P<\/jats:italic> = 0.02), lifetime history of alcohol use disorder (<jats:italic>P<\/jats:italic> = 0.02) and initiation of an anticonvulsant at study entry (<jats:italic>P<\/jats:italic> = 0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The introduction of anticonvulsants for a recent\u2010onset manic or mixed episode may be associated with an increased risk of <jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content>. Further <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> studies must determine whether this link is causal.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12709","type":"journal-article","created":{"date-parts":[[2017,2,12]],"date-time":"2017-02-12T07:46:49Z","timestamp":1486885609000},"page":"470-478","source":"Crossref","is-referenced-by-count":10,"title":["Anticonvulsants and suicide attempts in bipolar I disorders"],"prefix":"10.1111","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3660-6640","authenticated-orcid":false,"given":"F.","family":"Bellivier","sequence":"first","affiliation":[{"name":"Inserm U1144 Paris France"},{"name":"Department of Psychiatry and Addition Medicine Assistance Publique \u2013 H\u00f4pitaux de Paris (APHP) GH Saint\u2010Louis \u2013 Lariboisi\u00e8re \u2013 F. 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