{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T20:31:13Z","timestamp":1781123473147,"version":"3.54.1"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,5,26]],"date-time":"2017-05-26T00:00:00Z","timestamp":1495756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["476529\/2012\u20103"],"award-info":[{"award-number":["476529\/2012\u20103"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["466722\/2014\u20101"],"award-info":[{"award-number":["466722\/2014\u20101"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003810","name":"Hospital de Cl\u00ednicas de Porto Alegre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003810","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>There is a lack of available information on the trajectories of attention\u2010deficit\/hyperactivity disorder (<jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content>) dimensions during adulthood. This study investigates the course and the predictors of change for each <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content> domain in a clinical sample of adults with <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Adults with <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content> (<jats:italic>n<\/jats:italic> = 344) were followed up for 7 years, with a final retention rate of 66.0%. Trajectories of inattention, hyperactivity, and impulsivity and their potential predictors were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On average, symptoms declined in all <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content> domains during follow\u2010up. Despite this, rises in inattentive, hyperactive, and impulsive symptoms were observed in approximately 13%, 25%, and 17% of patients respectively. Different predictors influenced the trajectory of each <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content> dimension. Oppositional defiant disorder and social phobia were associated with the maintenance of symptoms, while alcohol use disorder was associated with both maintenance and rise of symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Unexpectedly, a rise in the symptoms after 7 years was not uncommon in adults with <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content>. Prevalent comorbidities have the potential to influence the neurodevelopment and the trajectory of <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content>. Therefore, such predictors should be investigated in population cohorts to better characterize the course of <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content>. Additionally, these findings may be relevant in prevention studies and in strategies for <jats:styled-content style=\"fixed-case\">ADHD<\/jats:styled-content> treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12757","type":"journal-article","created":{"date-parts":[[2017,5,26]],"date-time":"2017-05-26T15:36:40Z","timestamp":1495813000000},"page":"210-219","source":"Crossref","is-referenced-by-count":21,"title":["Trajectories of attention\u2010deficit\/hyperactivity disorder dimensions in adults"],"prefix":"10.1111","volume":"136","author":[{"given":"R. G.","family":"Karam","sequence":"first","affiliation":[{"name":"ADHD Outpatient Clinic Hospital de Cl\u00ednicas de Porto Alegre Porto Alegre Brazil"},{"name":"Department of Psychiatry Faculdade de Medicina Federal University of Rio Grande do Sul Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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