{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:22:15Z","timestamp":1790256135426,"version":"4.1.0"},"reference-count":102,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:00:00Z","timestamp":1500422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["223273"],"award-info":[{"award-number":["223273"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["K2014\u201062X\u201014647\u201012\u201051"],"award-info":[{"award-number":["K2014\u201062X\u201014647\u201012\u201051"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["K2010\u201061P\u201021568\u201001\u20104"],"award-info":[{"award-number":["K2010\u201061P\u201021568\u201001\u20104"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001729","name":"Stiftelsen f\u00f6r\u00a0Strategisk Forskning","doi-asserted-by":"publisher","award":["KF10\u20100039"],"award-info":[{"award-number":["KF10\u20100039"]}],"id":[{"id":"10.13039\/501100001729","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To confirm prior findings that the larger the maximum monthly increase in solar insolation in springtime, the younger the age of onset of bipolar disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Data were collected from 5536 patients at 50 sites in 32 countries on six continents. Onset occurred at 456 locations in 57 countries. Variables included solar insolation, birth\u2010cohort, family history, polarity of first episode and country physician density.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant, inverse association between the maximum monthly increase in solar insolation at the onset location, and the age of onset. This effect was reduced in those without a family history of mood disorders and with a first episode of mania rather than depression. The maximum monthly increase occurred in springtime. The youngest birth\u2010cohort had the youngest age of onset. All prior relationships were confirmed using both the entire sample, and only the youngest birth\u2010cohort (all estimated coefficients<jats:italic>P<\/jats:italic>&lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A large increase in springtime solar insolation may impact the onset of bipolar disorder, especially with a family history of mood disorders. Recent societal changes that affect light exposure (<jats:styled-content style=\"fixed-case\">LED<\/jats:styled-content>lighting, mobile devices backlit with<jats:styled-content style=\"fixed-case\">LED<\/jats:styled-content>s) may influence adaptability to a springtime circadian challenge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12772","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T11:54:26Z","timestamp":1500465266000},"page":"571-582","source":"Crossref","is-referenced-by-count":32,"title":["Solar insolation in springtime influences age of onset of bipolar I disorder"],"prefix":"10.1111","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2666-859X","authenticated-orcid":false,"given":"M.","family":"Bauer","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Psychotherapy University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Glenn","sequence":"additional","affiliation":[{"name":"ChronoRecord Association Fullerton CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Alda","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Dalhousie University Halifax NS Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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