{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:24:02Z","timestamp":1789507442074,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1037196"],"award-info":[{"award-number":["1037196"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the level of agreement across a set of evidence\u2010based guidelines for management of the unipolar depressive disorders and with a focus on physical treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A literature search was undertaken using the terms \u2018depression\u2019, \u2018depressive\u2019 and \u2018guidelines\u2019, using PubMed, Cochrane Database of Systematic Reviews and the National Guideline Clearinghouse. Twelve national psychiatric or professional guideline\u2010producing organizations were identified from the period 2007\u20132017, with guidelines qualitatively reviewed by two assessors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For major depressive disorder (MDD), there was general consensus to use an antidepressant (AD) in cases of greater severity, although disagreement on AD use in mild to moderate depression. There was some agreement on choice of AD class in first\u2010line treatment recommendations, though great variability in second\u2010 and third\u2010line management particularly in recommended augmentation and combined AD strategies. Electroconvulsive therapy was considered in all but one guideline, with other neurostimulation treatments being less consistently covered and with variable recommendations. Finally, there was low consistency in the management of dysthymia, persistent depressive disorder and treatment resistant depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our review identifies varying levels of consistency in guideline recommendations. Strategies to improve reliability in guideline formulation should also improve their validity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.12878","type":"journal-article","created":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T01:21:32Z","timestamp":1522027292000},"page":"459-471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Comparison of guidelines for the treatment of unipolar depression: a focus on pharmacotherapy and neurostimulation"],"prefix":"10.1111","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2976-822X","authenticated-orcid":false,"given":"A. J.","family":"Bayes","sequence":"first","affiliation":[{"name":"School of Psychiatry UNSW Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3424-5519","authenticated-orcid":false,"given":"G. B.","family":"Parker","sequence":"additional","affiliation":[{"name":"School of Psychiatry UNSW Sydney NSW Australia"},{"name":"Black Dog Institute Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12717"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535"},{"key":"e_1_2_9_4_1","volume-title":"Practice guideline for the treatment of patients with major depressive disorder","author":"American Psychiatric Association","year":"2010"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881115581093"},{"key":"e_1_2_9_6_1","unstructured":"BMJ Best Practice.Depression in adults. London: BMJ 2016. Available at:http:\/\/bestpractice.bmj.com\/best-practice\/monograph\/55."},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743716659417"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743716660033"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743716660290"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743716659276"},{"key":"e_1_2_9_11_1","volume-title":"VA\/DoD clinical practice guideline for the management of major depressive disorder","author":"Management of Major Depressive Disorder Working Group","year":"2016"},{"key":"e_1_2_9_12_1","unstructured":"German Society for Psychiatry Psychotherapy and Neurology (DGPPN) et al. (Eds) for the Guideline Group Unipolar Depression.S3\u2010guideline\/national disease management guideline unipolar depression \u2010 short version 1st edition version 5. Berlin: DGPPN 2009. Available at:http:\/\/www.leitlinien.de\/mdb\/downloads\/nvl\/depression\/archiv\/unipolare-depression-kurz-engl-1.3.pdf."},{"key":"e_1_2_9_13_1","volume-title":"The treatment and management of depression in adults (updated edition) (National Clinical Practice Guideline 90)","author":"National Institute for Health and Care Excellence","year":"2010"},{"key":"e_1_2_9_14_1","unstructured":"National Institute for Health and Care Excellence.Depression in adults: recognition and management (Clinical Guideline 90). London: NICE 2009. Available at:www.nice.org.uk\/guidance\/cg90."},{"key":"e_1_2_9_15_1","unstructured":"National Institute for Health and Care Excellence.Repetitive transcranial magnetic stimulation for depression (Interventional Procedures Guidance 542). London: NICE 2015. Available at:www.nice.org.uk\/guidance\/ipg542."},{"key":"e_1_2_9_16_1","unstructured":"National Institute for Health and Care Excellence.Transcranial direct current stimulation (tDCS) for depression (Interventional Procedures Guidance 530). London: NICE 2015. Available at:www.nice.org.uk\/guidance\/ipg530."},{"key":"e_1_2_9_17_1","unstructured":"National Institute for Health and Care Excellence.Vagus nerve stimulation for treatment\u2010resistant depression (Interventional Procedures Guidance 330). London: NICE 2009. Available at:www.nice.org.uk\/guidance\/ipg330."},{"key":"e_1_2_9_18_1","unstructured":"National Institute for Health and Care Excellence.Guidance on the use of electroconvulsive therapy (Technology Appraisal Guidance 59). London: NICE 2003. Available at:www.nice.org.uk\/guidance\/ta59."},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004867415617657"},{"key":"e_1_2_9_20_1","unstructured":"Working Group of the Clinical Practice Guideline on the Management of Depression in Adults.Clinical practice guideline on the management of depression in adults. Santiago de Compostela: Spanish National Health Service Galician Agency for Health Technology Assessment (avalia\u2010t) 2014."},{"key":"e_1_2_9_21_1","volume-title":"Texas medication algorithm project procedural manual: major depressive disorder algorithms","author":"Suehs B","year":"2008"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/15622975.2013.804195"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/15622975.2014.1001786"},{"key":"e_1_2_9_24_1","volume-title":"Pharmacological treatment of mental disorders in primary care","author":"World Health Organization","year":"2009"},{"key":"e_1_2_9_25_1","volume-title":"Duration of antidepressant treatment","author":"World Health Organization","year":"2012"},{"key":"e_1_2_9_26_1","volume-title":"Antidepressants (tricyclic antidepressants and selective serotonin reuptake inhibitors) in treatment of adults with depression","author":"World Health Organization","year":"2012"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/qhc.12.1.18"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.7326\/M15-1813"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2017.0044"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4246"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.7.1370"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.3.469"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facps.12878","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.12878","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T10:48:09Z","timestamp":1695034089000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acps.12878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,25]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/acps.12878"],"URL":"https:\/\/doi.org\/10.1111\/acps.12878","archive":["Portico"],"relation":{},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,25]]},"assertion":[{"value":"2018-02-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}