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All subjects were evaluated with structured diagnostic interviews, and diagnoses of relatives were made blind to the diagnoses of probands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Relatives of probands with <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\u2010I disorder had high rates of <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\u2010I, and relatives of probands with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> had high rates of <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> irrespective of the comorbidity with the other disorder. Relatives of probands with the combined condition of <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\u2010I had high rates of the combined condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The finding of cosegregation between <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\u2010I disorder and <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> is consistent with the hypothesis that the combined condition represents a distinct subtype of either disorder.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.13013","type":"journal-article","created":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T11:44:50Z","timestamp":1550058290000},"page":"361-368","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Comorbidity of bipolar I disorder and conduct disorder: a familial risk analysis"],"prefix":"10.1111","volume":"139","author":[{"given":"J.","family":"Wozniak","sequence":"first","affiliation":[{"name":"Pediatric Psychopharmacology Program Division of Child Psychiatry Massachusetts General Hospital Boston MA USA"},{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Wilens","sequence":"additional","affiliation":[{"name":"Pediatric Psychopharmacology Program Division of Child Psychiatry Massachusetts General Hospital Boston MA USA"},{"name":"Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"DiSalvo","sequence":"additional","affiliation":[{"name":"Pediatric Psychopharmacology Program Division of Child Psychiatry Massachusetts General Hospital Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4411-3288","authenticated-orcid":false,"given":"A.","family":"Farrell","sequence":"additional","affiliation":[{"name":"Pediatric Psychopharmacology Program Division of Child Psychiatry Massachusetts General Hospital Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Wolenski","sequence":"additional","affiliation":[{"name":"Pediatric Psychopharmacology Program Division of Child Psychiatry Massachusetts General Hospital Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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