{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:43:03Z","timestamp":1787013783752,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T00:00:00Z","timestamp":1559865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To investigate whether early improvement, measured after two electroconvulsive therapy (ECT) sessions, is a good predictor of eventual remission in severely depressed in\u2010patients receiving\n                      <jats:styled-content style=\"fixed-case\">ECT<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A prospective cohort study was performed that included 89 major depressive disorder in\u2010patients treated with bilateral\n                      <jats:styled-content style=\"fixed-case\">ECT<\/jats:styled-content>\n                      . Sensitivity, specificity, and predictive values were computed for various definitions of early improvement (15%, 20%, 25%, and 30% reduction on the Montgomery Asberg depression rating scale (MADRS) score) after 1\u00a0week (i.e. two sessions) of\n                      <jats:styled-content style=\"fixed-case\">ECT<\/jats:styled-content>\n                      regarding prediction of remission (final\n                      <jats:styled-content style=\"fixed-case\">MADRS<\/jats:styled-content>\n                      score\u00a0\u2264\u00a09).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A 15% reduction in\n                      <jats:styled-content style=\"fixed-case\">MADRS<\/jats:styled-content>\n                      score appeared to be the best definition of early improvement, with modest sensitivity (51%) and relatively good specificity (79%). Kaplan\u2013Meier analysis showed a more than 2\u2010week shorter time to remission in patients with early improvement compared with patients lacking early improvement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Early improvement during an\n                      <jats:styled-content style=\"fixed-case\">ECT<\/jats:styled-content>\n                      course may be assessed after two\n                      <jats:styled-content style=\"fixed-case\">ECT<\/jats:styled-content>\n                      sessions. Such improvement, defined as a 15% reduction in the\n                      <jats:styled-content style=\"fixed-case\">MADRS<\/jats:styled-content>\n                      score, is a moderately sensitive predictor for eventual remission in an in\u2010patient population with severe major depression.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13054","type":"journal-article","created":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T20:44:08Z","timestamp":1558212248000},"page":"189-195","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Improvement after two sessions of electroconvulsive therapy predicts final remission in in\u2010patients with major depression"],"prefix":"10.1111","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6611-6597","authenticated-orcid":false,"given":"T. K.","family":"Birkenhager","sequence":"first","affiliation":[{"name":"Department of Psychiatry Erasmus Medical Centre Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Roos","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Erasmus Medical Centre Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. M.","family":"Kamperman","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Erasmus Medical Centre Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12705-5"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.141.8.1010b"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e3181ee0f5f"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14r09528"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2017.28"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v65n0406"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.164.1.106"},{"key":"e_1_2_9_9_1","first-page":"1","article-title":"Mini\u2010compendium of rating scales for states of anxiety depression mania schizophrenia with corresponding DSM\u2010III syndromes","volume":"326","author":"Bech P","year":"1986","journal-title":"Acta Psychiatr Scand Suppl"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02245860"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2018.10.105"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2018.03.014"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2018.11.014"},{"key":"e_1_2_9_14_1","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2015.15030372"},{"key":"e_1_2_9_16_1","first-page":"1","article-title":"Bitemporal v high\u2010dose unilateral electroconvulsive therapy for depression: a systematic review and meta\u2010analysis of randomized controlled trials","volume":"47","author":"Kolshus E","year":"2016","journal-title":"Psychol Med"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.134.4.382"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2006.04.008"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21979"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-6646-9"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.07040574"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.07m03780"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2008.10.011"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-014-3765-1"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12962"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.147.8.1029"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Facps.13054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.13054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acps.13054","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.13054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T04:05:26Z","timestamp":1694145926000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acps.13054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,7]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/acps.13054"],"URL":"https:\/\/doi.org\/10.1111\/acps.13054","archive":["Portico"],"relation":{},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,7]]},"assertion":[{"value":"2019-05-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}