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Factors most strongly linked to poor outcome were comorbid obsessive\u2013compulsive disorder, alcohol and\/or substance misuse, and\/or psychosis (symptoms or syndromes).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Network analysis can offer important additional insights to prospective studies of predictors of Li treatment outcomes. It appears to especially help in further clarifying the role of family history of BD (i.e. its direct and indirect associations) and highlighting the positive and negative associations of different subtypes of anxiety disorders with Li response, particularly the little\u2010known negative association between Li response and obsessive\u2013compulsive disorder.<\/jats:p><\/jats:sec>","DOI":"10.1111\/acps.13163","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T13:57:32Z","timestamp":1582034252000},"page":"522-533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Can network analysis shed light on predictors of lithium response in bipolar I disorder?"],"prefix":"10.1111","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7203-8601","authenticated-orcid":false,"given":"J.","family":"Scott","sequence":"first","affiliation":[{"name":"Institute of Neuroscience Newcastle University Newcastle UK"},{"name":"Universit\u00e9 Paris Diderot and INSERM UMRS1144 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3660-6640","authenticated-orcid":false,"given":"F.","family":"Bellivier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Diderot and INSERM UMRS1144 Paris France"},{"name":"D\u00e9partement de Psychiatrie et de M\u00e9decine Addictologique AP\u2010HP GH Saint\u2010Louis\u2010Lariboisi\u00e8re\u2010F. 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