{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T12:44:18Z","timestamp":1772714658445,"version":"3.50.1"},"reference-count":70,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Despite the proven efficacy and safety of ECT, there is still concern about the possible cognitive side effects of ECT in older patients. In this study, we aimed to characterize the long\u2010term cognitive effects of ECT in patients with late\u2010life depression (LLD) from before the start until 4\u00a0years after the index ECT course.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fourty one patients aged 55\u00a0years and older with a unipolar depression, referred for ECT, were included. The neuropsychological test battery was assessed prior to ECT, 6\u00a0months, 1\u00a0year, 2\u00a0years, 3\u00a0years, and 4\u00a0years after the last ECT session.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We did not find any statistically significant cognitive changes from before the start to 4\u00a0years after ending the ECT course. Although we could not detect cognitive changes at group level, we found clinically important differences on an individual level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cognitive performance in patients with LLD runs a stable course from before the start of ECT until 4\u00a0years after the index course. At an individual level, however, both cognitive decline and improvement can be witnessed. Older patients can tolerate ECT and most of them will not experience long\u2010term cognitive side effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13252","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T01:37:56Z","timestamp":1604540276000},"page":"141-150","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Neurocognitive functioning after electroconvulsive therapy in late\u2010life depression: A 4\u2010year prospective study"],"prefix":"10.1111","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6351-1543","authenticated-orcid":false,"given":"Jasmien","family":"Obbels","sequence":"first","affiliation":[{"name":"Academic Center for ECT and Neuromodulation (AcCENT University Psychiatric Center KU Leuven KU Leuven \u2013 University of Leuven Kortenberg Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristof","family":"Vansteelandt","sequence":"additional","affiliation":[{"name":"Academic Center for ECT and Neuromodulation (AcCENT University Psychiatric Center KU Leuven KU Leuven \u2013 University of Leuven Kortenberg Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filip","family":"Bouckaert","sequence":"additional","affiliation":[{"name":"Old\u2010age Psychiatry University Psychiatric Center KU Leuven KU Leuven \u2013 University of Leuven Kortenberg Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annemiek","family":"Dols","sequence":"additional","affiliation":[{"name":"Department of Old Age Psychiatry Amsterdam Public Health Research Institute Amsterdam Neuroscience GGZ inGeest\/Amsterdam UMC, Location VUmc Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Stek","sequence":"additional","affiliation":[{"name":"Department of Old Age Psychiatry Amsterdam Public Health Research Institute Amsterdam Neuroscience GGZ inGeest\/Amsterdam UMC, Location VUmc Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esm\u00e9e","family":"Verwijk","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology Neuropsychology Department Academic Medical Center Amsterdam UMC Amsterdam The Netherlands"},{"name":"Department of Psychology, Brain &amp; Cognition University of Amsterdam Amsterdam The Netherlands"},{"name":"ECT Department Parnassia Psychiatric Institute The Hague The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0650-415X","authenticated-orcid":false,"given":"Pascal","family":"Sienaert","sequence":"additional","affiliation":[{"name":"Academic Center for ECT and Neuromodulation (AcCENT University Psychiatric Center KU Leuven KU Leuven \u2013 University of Leuven Kortenberg Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.Mental health of older adults.https:\/\/www.who.int\/en\/news\u2010room\/fact\u2010sheets\/detail\/mental\u2010health\u2010of\u2010older\u2010adults. Accessed April 15 2020"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e31822001c1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51555.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.13134"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.151.11.1657"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000243"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000320"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.944"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.12050648"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2016.86"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2017.28"},{"key":"e_1_2_8_13_1","first-page":"39","article-title":"Age\u2010dependent effects of electroconvulsive therapy on memory","volume":"9","author":"Zervas IM","year":"1993","journal-title":"J ECT"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200403000-00008"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000661"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2019.10.003"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1989"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0b013e318165c7b0"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2016.02.053"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2018.12.599"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2010.06.009"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610213001932"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.20144"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12942"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2019.04.006"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.150.6.896"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-8343(98)00015-2"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200409000-00010"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200406000-00003"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e318170a6fa"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_2_8_32_1","volume-title":"Dementia Rating Scale: Professional Manual","author":"Mattis S","year":"1988"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2016.09.005"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.134.4.382"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(82)90033-4"},{"key":"e_1_2_8_37_1","first-page":"22","article-title":"The Mini\u2010International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM\u2010IV and ICD\u201010","volume":"59","author":"Sheehan DV","year":"1998","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.930080606"},{"key":"e_1_2_8_39_1","volume-title":"Handleiding Amsterdamse Dementie Screening","author":"Lindeboom J","year":"1989"},{"key":"e_1_2_8_40_1","volume-title":"Handleiding: Visuele Associatie Test","author":"Lindeboom J","year":"2003"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.5334\/pb.1023"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12439-016-0189-x"},{"key":"e_1_2_8_43_1","volume-title":"Linear Mixed Models for Longitudinal Data","author":"Verbeke G","year":"2000"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470510445"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.03.152"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-9452(08)70878-5"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617710000706"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.10m05973gry"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/13854046.2014.958536"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000385"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1037\/0882-7974.17.2.179"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12374"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1017\/S109285290002753X"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707001134"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709990833"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.4510"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.895"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.JGP.0000203130.45421.69"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.90.3.213"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707001249"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.59.11.1737"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e328356c368"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.111.101931"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2018.00397"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(18)30056-7"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0b013e3181616c26"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1999.tb02570.x"},{"key":"e_1_2_8_68_1","volume-title":"Trail\u2010Making Test","author":"Reitan RM","year":"1979"},{"key":"e_1_2_8_69_1","volume-title":"Groninger Intelligentie Test (GIT)","author":"Ploeg FAE","year":"1983"},{"key":"e_1_2_8_70_1","volume-title":"L\u2019examen Clinique en Psychologie","author":"Rey A","year":"1964"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.73.2.126"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.13252","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acps.13252","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.13252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T07:34:53Z","timestamp":1693640093000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acps.13252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,31]]},"references-count":70,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/acps.13252"],"URL":"https:\/\/doi.org\/10.1111\/acps.13252","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/ACPS.13252\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13252\/v1\/review1","asserted-by":"object"}]},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,31]]},"assertion":[{"value":"2020-09-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}